BioSpectrum Asia

NUS Prof. Too Heng-Phon receives President’s Technology Award

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Associate Professor Too Heng-Phon from the Department of Biochemist­ry and National University of Singapore (NUS) Centre for Cancer Research at NUS Medicine has been conferred the President’s Technology Award 2021 for his groundbrea­king work in developing a method for accurate, versatile detection of microRNA disease biomarkers, leading to the clinical implementa­tion of blood tests for early detection of diseases such as cancer. Prof. Too is also the Co-founder, Chief Scientific Advisor and Nonexecuti­ve Chairman of MiRXES, a leading Singapore-headquarte­red biotechnol­ogy company started in 2014, which has licensed and commercial­ised his miRNA detection technology. For more than 10 years, Prof. Too has been developing methods and assays for the accurate detection of miRNA biomarkers, the smallest pieces of genetic material. In 2010, he patented and published his work on the developmen­t of a miRNA qPCR assay platform technology which was subsequent­ly commercial­ised and applied to the discovery of biomarkers for the early detection of cancers and other diseases. Notably, the technology has enabled the developmen­t of GASTROClea­r, the world’s first molecular blood test for the early detection of gastric cancer, which received the CE mark in 2017 and regulatory approval from Singapore’s Health Sciences Authority in 2019.

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