BioSpectrum Asia

Nasal spray to fight COVID-19 heads to clinical trial in Australia

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An at-home nasal spray treatment for COVID-19 will be put to the test by Melbourne biomedical researcher­s, as the University of Melbourne and Monash University in Australia receive $4.2 million to establish a six-month clinical trial lead by Northern Hospital in collaborat­ion with Oxford University. Heparin, a widely used blood-thinning drug to treat or prevent blood clots forms the base of the nasal spray treatment that is simple to administer, stable at room temperatur­e and available globally. The IntraNasal HEpaRin Trial (INHERIT) will be led by the Northern Hospital, using an innovative monitoring and treatment platform that allows researcher­s to access and remotely treat patients within 24 hours of their diagnosis, speeding up treatment and providing monitoring through portable oximeter devices that measure oxygen levels in blood. With the help of University of Melbourne, Monash and Oxford University researcher­s, the team has confirmed Heparin can block the transmissi­on of COVID-19 and prevent infection, making way for clinical trials to begin.

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