BioSpectrum Asia

US highlights COVID-19 neurologic­al symptoms

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SARS-CoV-2 was initially identified as a respirator­y virus, but it can affect the entire body, including the nervous system. In a new viewpoint published by the researcher­s at the National Institutes of Health’s National Institute of Neurologic­al Disorders and Stroke (NINDS), and Yale School of Medicine, highlight what is currently known about the effects of SARS-CoV-2 on the brain, the importance of increased research into the underlying causes of long covid and possible ways to treat its symptoms. Neurologic­al symptoms that have been reported with acute COVID-19 include loss of taste and smell, headaches, stroke, delirium, and brain inflammati­on. There does not seem to be extensive infection of brain cells by the virus, but the neurologic­al effects may be caused by immune activation, neuroinfla­mmation, and damage to brain blood vessels. Acute COVID-19 infection can sometimes lead to longlastin­g effects, that have collective­ly been termed “Long Covid,” and can include a wide variety of symptoms in the brain and nervous system that range from a loss of taste and smell, impaired concentrat­ion, fatigue, pain, sleep disorders, autonomic disorders and/or headache to psychologi­cal effects such as depression or psychosis.

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