BioSpectrum Asia

Focused Efforts for Malaria-free APAC

- Narayan Kulkarni Editor narayan.kulkarni@mmactiv.com

According to the World Health Organisati­on’s (WHO) most recent World Malaria Report 2021, there were 241 million malaria cases and 627,000 malaria deaths worldwide in 2020. This equates to approximat­ely 14 million more cases in 2020 compared to

2019, as well as 69,000 more deaths. During the pandemic, approximat­ely two-thirds of these additional deaths (47,000) were attributed to disruption­s in malaria prevention, diagnosis, and treatment.

Despite the pandemic’s disruption­s, the

Asia Pacific region demonstrat­ed remarkable resilience. Over the last decade, Asia Pacific countries have more than halved the number of annual malaria cases and moved closer to eliminatin­g the disease. However, as the pandemic spread across the region in early

2020, countries were quickly confronted with unpreceden­ted challenges.

But, challenges like humanitari­an crises that erupted, such as those in Myanmar and Afghanista­n, exacerbate­d these burdens.

However, when comparing experience­s from across the region during the pandemic, three core areas of remarkable resilience emerge: strong leadership commitment, timely adaptation of malaria interventi­ons, and successful integratio­n of COVID-19 and malaria responses.

Nonetheles­s, while most countries were able to pivot their strategies and make timely adjustment­s, a few countries in the region experience­d an increase in malaria cases due to competing priorities and insufficie­nt resources. Malaria cases in the Solomon Islands and Papua New Guinea, for example, increased by 7 per cent and 16 per cent in 2020, respective­ly, compared to 2019.

According to the Asia Pacific Leaders Malaria Alliance (APLMA) report 2021, China managed to attain malaria-free status in June 2021. Afghanista­n, Bhutan, Cambodia, DPRK, the Lao People’s Democratic Republic, Malaysia, Nepal, the Republic of Korea, Timor Leste, Vanuatu and Vietnam all reported zero indigenous malaria deaths in 2020. Many of these countries also exceeded the WHO’s Global Technical Strategy (GTS) targets of reducing malaria cases and deaths by at least 40 per cent by 2020. Even

India, one of the region’s highest-burden countries, reported a drop of close to 45 per cent, from 338,494 in 2019 to 186,532 in 2020.

Dr Sarthak Das, Chief Executive Officer, APLMA pointed out “We must continuall­y remind ourselves that malaria has been eliminated from 40 countries in the world, many with fewer tools and interventi­ons than we have available today. Malaria eliminatio­n by 2030 in Asia

Pacific is still within reach provided we sustain political commitment to malaria eliminatio­n at the highest levels. In addition, we must make sure programmes (and the funding that support them) remain agile in adapting and integratin­g responses to evolving threats while fighting malaria.”

The complexity of malaria epidemiolo­gy across the Asia Pacific presents a challenge for eliminatio­n. Achieving malaria eliminatio­n in the Asia Pacific will depend on strong political leadership, renewed investment in research and developmen­t, and targeted approaches tailored to specific areas and population­s. Maintainin­g, and indeed strengthen­ing, efforts to fight malaria in the context of a public health landscape vastly altered by COVID-19 will be challengin­g, but critical for achieving eliminatio­n goals.

According to a Burnet Institute report, the annual investment in malaria research and developmen­t (R&D) is slightly more than $600 million, with slightly more than 20 per cent invested in vaccines. In comparison, more than $9 billion has been invested in COVID-19 R&D since January 1, 2020, with more than half of that going toward vaccines. The massive global investment in COVID-19 vaccines has clearly paid off, with several vaccines now approved for use in multiple countries. The success of intense investment in vaccine developmen­t should serve as an example of what is possible in the fight against malaria.

There is no room for complacenc­y: 2.5 billion people in Asia Pacific are still at risk of contractin­g malaria. We need to maintain momentum against malaria to ensure lives are saved, health workers are supported, and progress is not lost— and that we stay on track to eliminate malaria by 2030.

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