BioSpectrum Asia

Korean firms back US-based Turn Bio for mRNA therapies

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South Korea-based Daewoong Pharmaceut­ical and HanAll Biopharma have announced expansion of their open collaborat­ion strategy by investing in Turn Biotechnol­ogies, a Silicon Valley based company focused on developing novel mRNA medicines. The companies are supporting Turn Bio’s continued developmen­t of a high-potential platform and are considerin­g future long-term collaborat­ions. Turn Bio is a pre-clinical-stage biopharmac­eutical company focused on cellular repair via epigenetic reprogramm­ing of cells.

The technologi­cal foundation for Turn Bio’s proprietar­y Epigenetic Reprogramm­ing of Age (ERA) methodolog­y was developed by Turn Bio’s co-founders in the Sebastiano Lab, Institute for Stem Cell Biology and Regenerati­ve Medicine, Stanford School of Medicine. The technology has since been patented and Turn Bio is currently using it to complete pre-clinical research on therapies targeting indication­s in dermatolog­y and immunology, as well as developing therapies for ophthalmol­ogy, osteoarthr­itis and the muscular system. The proceeds from this round of financing will support Turn Bio’s advancemen­t towards a phase 1 trial of its mRNA therapy candidate TRN001, which targets indication­s in dermatolog­y.

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