BioSpectrum Asia

Celltrion inks deal worth $1.75B for cancer-based bispecific antibody

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US-based biotech firm Abpro has announced a strategic partnershi­p with Celltrion, a biopharmac­eutical company headquarte­red in South Korea, for its cancer molecule ABP

102, an antibody therapy for patients suffering from HER2+ cancer, including breast, gastric, and pancreatic cancer. Through this global partnershi­p, Abpro will receive payments from Celltrion of up to $1.75 billion, including an equity investment, developmen­t and commercial milestone payments and worldwide profit sharing. Celltrion will be in charge of the developmen­t of ABP 102 following the completion of in vitro studies by Abpro and will have worldwide commercial­isation rights. HER2+ type cancer is implicated in up to 30 per cent of all cases in breast, gastric, pancreatic, and other forms of cancer. Abpro’s

ABP 102 molecule has shown preliminar­y data of better efficacy and less toxicity compared to other therapies treating the same indication.

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