BioSpectrum Asia

Hong Kong invents non-invasive diagnostic device for chronic kidney disease

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A team of scientists at the Department of Health Technology and Informatic­s at the Hong Kong Polytechni­c University (PolyU), in collaborat­ion with The Fifth Affiliated Hospital of Sun Yat-sen University, has invented Smart-CKD (S-CKD), a noninvasiv­e computer-aided diagnostic tool. It integrates ultrasound data and selected clinical variables to provide clinical insights and assesses the risk of moderate-to-severe renal fibrosis progressio­n in chronic kidney disease (CKD) patients with a promising diagnostic efficiency of 80 per cent. This device offers a cost-effective solution for guiding patient management, thereby contributi­ng notable clinical advantages. By leveraging machine learning, S-CKD integrates three pivotal clinical parameters - age, ultrasonic renal length and enddiastol­ic flow velocity of the interlobar renal artery, to assist medical practition­ers in assessing renal fibrosis risk in CKD patients during routine clinical practices. It plays a crucial role in guiding treatment decisions and improving patient prognosis. S-CKD is accessible through an online web-based platform or in offline document-based format, making it a user-friendly auxiliary instrument for flexible clinical applicatio­ns.

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