Need to diagnose the right allergens
Growing industrialization and fast changing biodiversity coupled with sedentary lifestyles are causing a surge in allergic diseases, especially among children in the country. The rising allergy rate among the population is alarming and calls for action. The best defense against allergic symptoms is to know what’s causing them and to avoid those triggers. This doesn’t necessarily mean cutting everything one is allergic to, out of life.
Allergy occurs when the reaction is believed to be mediated by Immunoglobulin E (IgE), which is one of the major mediators of immediate hypersensitivity reaction that underlie atopic conditions such as asthma and anaphylaxis. The allergen could be in the air, chemicals that one comes in contact with or the food that one eats.
As per World Allergy Organization (WAO) about 20 to 30 per cent of people in India have one or more allergic diseases and the prevalence is rising dramatically. The burden of allergic diseases in India has been on an uprising trend in terms of prevalence and severity. These allergic diseases include asthma, rhinitis, anaphylaxis, drug, food and insect allergy, eczema and urticaria and angioedema. Allergies are common; some allergy symptoms last for a few minutes, while others may continue for months or more, and some allergies can also become life threatening. Out of this, the prevalence of asthma and allergic rhinitis (AR) are the two major forms of allergies world-wide.
Everyone has their own unique combination of allergic triggers and not all of them are obvious. While most allergic reactions are only mild to moderate in severity (and can be treated with antihistamines), some can be life-threatening and require emergency medical treatment.
The most severe, systemic allergic reactions are known as anaphylaxis. People with known severe allergies should have an emergency management plan that includes an adrenaline auto-injector for emergency use. In the case of food allergy, if the probability of an allergic reaction is low, people are given a food challenge where increasing amounts of the offending food are administered while the person is closely observed for any signs of an allergic reaction. Of course, it can result in a reaction which is why this is conducted under close observation.
An allergy can broadly be confirmed by two techniques. A
Skin Prick Test (SPT) or a blood test (In-vitro) that checks whether their immune system has produced antibodies to an allergen. The discovery of IgE is a breakthrough in the field of allergy and immunology. Several refinements in diagnostic modalities have resulted in highly sensitive and accurate systems, allowing measurements of IgE antibodies to hundreds of allergens. PhadiaTop is an advanced qualitative serum specific IgE assay test for detection of allergic sensitization that works to dramatically improve the management of allergy and autoimmune diseases by providing healthcare professionals with superior diagnostic techniques and clinical expertise.
Allergy blood tests are wellthought-out and safe, since the person is not exposed to any allergens during the testing procedure.
Many common illnesses that display symptoms commonly associated with allergy have different etiologies and, therefore, different treatments. A common blood sample can help you see whether these symptoms are due to allergy. Rather than identifying just one allergen, believed to have initiated the allergic response in the body, it is of utmost importance to map all the allergens to which patients are sensitized and evaluate how the allergens together can aggravate the allergic symptoms in the patient. Several other factors such as age, degree of atopy, allergen load, type of symptoms and indoor environment, along with tests that are accurate and reliable, can provide doctors with adequate information needed for the diagnosis and management of allergic diseases.
ALLERGY BLOOD TESTS ARE WELL- THOUGHT-OUT
AND SAFE, SINCE THE PERSON IS NOT EXPOSED TO ANY ALLERGENS DURING THE TESTING
Managing Director & VP/GM,Thermo Fisher Scientific, India, SouthAsia & Middle East
AMIT CHOPRA,Managing Director & VP/GM, Thermo Fisher Scientific, India, SouthAsia & Middle East