Sci­en­tists cre­ate biosen­sor for de­tect­ing fun­gal in­fec­tion

BioSpectrum (India) - - SCIENCE NEWS -

A team of re­searchers from CSIR – Cen­tre for Cel­lu­lar and Molec­u­lar Bi­ol­ogy (CCMB), In­dian In­sti­tute of Tech­nol­ogy Guwahati and MNR Den­tal Col­lege & Hos­pi­tal, Hyderabad have de­vel­oped an elec­tro­chem­i­cal nanobiosen­sor that can ef­fi­ciently di­ag­nose in­va­sive as­pergillo­sis. The re­searchers used gold nanopar­ti­cles, a polysac­cha­ride called chi­tosan, a gold elec­trode and a chem­i­cal called 1,6-Hex­anedithiol (HDT) to as­sem­ble the biosen­sor. It works by de­tect­ing gliP, a gene found ex­clu­sively in the Aspergillus species. The biosen­sor de­vel­oped by the re­searchers is quicker and cost-ef­fec­tive as com­pared to the ex­ist­ing meth­ods, al­low­ing early de­tec­tion and af­ford­abil­ity to pa­tients. The re­searchers hope that they can soon have a mar­ket-ready prod­uct. This study was sup­ported by grants from the Depart­ment of Science and Tech­nol­ogy (DST), Science and En­gi­neer­ing Re­search Board (SERB), Gov­ern­ment of In­dia.

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