Business Standard

A few clicks that can detect breast cancer

Niramai offers thermo analytics-based cancer screening solution that can help detect breast cancer early, reports Veena Mani & Ranju Sarkar

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Niramai offers thermo analytics based cancer screening solution that can help detect breast cancer early. VEENA MANI & RANJU SARKAR write

Every year breast cancer claims the lives of over 76,000 women in India and 500,000 globally. A majority of them can be cured and saved if detected early. The current technique of testing like mammograph­y is radiation-based and painful, and not effective for women below 45.

A Bengaluru-based health analytics start-up, Niramai, is using a new technique to detect breast cancer early. It combines an existing technique for cancer screening, thermograp­hy with machine learning, to develop a statistica­l model for cancer diagnosis.

Niramai calls it Thermalyti­x, a fusion of analytics over thermal imaging, and has applied for patents. It is a disruptive technique that can detect breast cancer early and costs only a tenth of what the existing tests do.

The start-up thinks its solution can overcome the cultural barriers and privacy concerns of women on cancer screening and can become a part of their preventive health check-up. “Niramai's solution is non-contact, non-invasive, safe, accurate and portable, and works for women of all age groups,” says Geetha Manjunath, chief executive and founder.

The company, working in research mode with two hospitals and a diagnostic lab, has tested the cancer-screening tool on 400 patients, and the early results are promising. Next, it would go for clinical trials on more patients. It is targeting a commercial launch by August.

Last week, it raised funds from investors, including pi Ventures, Ankur Capital, Axilor Ventures, 500 Start-ups, and Flipkart co-founder Binny Bansal.

Manish Singhal, founding partner, pi Ventures, feels that Niramai can become the go-to solution for early-stage diagnosis for breast cancer globally. That is a huge opportunit­y, not just from a business perspectiv­e but also they can help save many lives. The technology Niramai, which stands for non-invasive risk assessment with machine intelligen­ce, uses a high-resolution thermal camera as a device and a cloud-hosted analytics solution to analyse the images. “The unique value propositio­n of Nirmai's solution is the ability to detect it early and in a completely privacy-sensitive way,” says Manjunath.

Niramai uses a patented methodolog­y called Thermalyti­x, which is a fusion of machine analytics over thermal imaging. The technique removes the accuracy limitation that existed in the highly sensitive medically proven method of detect- ing cancer called ther- mography and makes it suitable to interpreta­tion by any clinician.

Machine learning is a branch of artificial intelligen­ce (AI), which uses data from a small group of patients along with their diagnosis to build a mathematic­al representa­tion of an expert doctor's brain that can help make decisions. This mathematic­al model is then applied on undiagnose­d patients data to predict the likelihood of a disease in the patient. Niramai’s tool uses AI to enable easy and accurate interpreta­tion of thermal images and intended to be used by a doctor. How it began This idea goes back to a few years. Founders Geetha Manjunath and Nidhi Mathur while working with Xerox India thought of bringing this technology to Indian women. They worked on imaging and engaged with hospitals in the process. Soon they began Niramai that can detect breast cancer with just a few clicks.

The patient is sent to a cold room where her body temperatur­e is regulated. After that, the patient is taken to the testing room where a device kept at a distance of three-feet captures the temperatur­e distributi­on, which is automatica­lly analysed by the Niramai tool. The analysis is based on the medical physiology of tumour tissues which behave differentl­y when there is malignancy. Opportunit­y According to an estimate, only a tenth of the two billion women who need diagnosis for breast cancer get their tests done. This gap is the opportunit­y for Niramai. The founders say the current technology available can only diagnose breast cancer once it has reached a critical stage, but their product can detect at an early stage.

Mathur, who is the chief operations officer, says that their competitio­n in India is not with any other diagnostic firm or technology, as most screening methods today look for lumps.

The global breast imaging equipment market, growing at a compounded rate of 8.5 per cent annually, is expected to reach $4.14 billion by 2021. In 2015, of the $2.6billion worth of breast imaging equipment sold, mammograph­y accounted for 50 per cent, while non-ionising modalities market was nearly $1billion, according to market surveys.

Nearly 140 million mammograph­y screenings are performed every year (each test costs around ~3,000 in India). And, 36 per cent of these require correlatio­n using another imaging modality. Around 2.7 billion women will need breast cancer screening by the next 15 years. Though path-breaking and cheaper, the new testing technique will have to go through the adoption cycle any new technology goes through.

Manish Singhal (pictured), founding partner, pi Ventures, says he feels Niramai can become the go-to solution for earlystage diagnosis for breast cancer globally

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 ??  ?? Geetha Manjunath (left)and Nidhi Mathur, co-founders of Niramai
Geetha Manjunath (left)and Nidhi Mathur, co-founders of Niramai

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