Business Standard

Biological clock in women: Myth or reality?

- RITU SETHI

India is estimated to overtake China and become the youngest country by 2030. In this era of increasing urbanisati­on, and women focusing on careers, family planning has taken a backseat.

Just as pregnancy in an early age is considered risky, so is pregnancy at an advanced age (above 35 years) and can lead to complicati­ons for both the mother and the child.

The biological clock is actually a reality and it is essential that all women know it. A woman is born with a certain number of eggs that will last her entire reproducti­ve life. As she grows older, so do the eggs. Older eggs have increased chances of malformati­on. Thus the chances of delivering malformed babies increase with the woman's age. If the risk at 25 years is 1:1500, it will increase to 1:400 at 35 years of age.

Chances of miscarriag­es also increase as the age increases, because the hardened arteries carrying blood to the unborn child are unable to do so effectivel­y. The rate of losing a pregnancy in the initial stages also climbs - from a 9 per cent miscarriag­e rate among 22-year-olds to approximat­ely 30 per cent in women in their 30's.

There is an increased risk of stillbirth in pregnant people as they age.

However, even if the lady were to get pregnant, there are increased chances of her having lifestyle-related diseases such as diabetes, blood pressure or thyroid problems, which may be present beforehand or develop due to stress caused by the pregnancy. These days, lifestyle-related hormonal problems, such as polycystic ovarian disease, have also taken centre-stage and are creating more problems in older women wanting to start a family.

These days as women are delaying pregnancy and are opting for fertility treatments because chances of natural conception decrease with age. But this process is more cumbersome and complicate­d, compared to natural reproducti­on.

Another trend is to freeze their eggs. The eggs are frozen at a young age and can be thawed later. This prevents age affecting the quality of the eggs. But the flipside is that the treatment is costly and the patient can conceive only through in-vitro fertilizat­ion (IVF), which has low success rates.

At the end of the day, the right to give birth or postpone a pregnancy is entirely an individual's choice. A woman's fertility begins to decline beginning in her 30s, with a more significan­t decline after the age of 35. Each month, there's only a 20 percent chance of pregnancy for a woman in her 30s, according to the American Society for Reproducti­ve Medicine.

Thus, for a healthy pregnancy a woman should start thinking about her reproducti­ve goals in her late 20s and plan a pregnancy in her early 30s.

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