Suc­ci­nate pro­duc­tion method that is re­new­able and ef­fi­cient

Chemical Industry Digest - - Renewables -

Suc­ci­nate is an ex­tremely use­ful raw in­gre­di­ent for petro­chem­i­cals, and there is high de­mand for a way of pro­duc­ing suc­ci­nate that is re­new­able and en­vi­ron­men­tally be­nign.

A Ja­panese re­searcher has dis­cov­ered that suc­ci­nate pro­duc­tion lev­els in­crease when cyanobac­te­ria are grown above the ideal tem­per­a­ture for cell growth. He used in­sights into the meta­bolic path­way engi­neer­ing to achieve the world’s most ef­fi­cient pro­duc­tion rate for bio-suc­ci­nate, as per the re­port by Kobe Univer­sity, Ja­pan.

The dis­cov­ery was made by Pro­fes­sor To­mo­hisa Ha­sunuma ( Kobe Univer­sity Grad­u­ate School of Sci­ence, Tech­nol­ogy and In­no­va­tion) as a Ja­pan Sci­ence and Tech­nol­ogy Agency Strate­gic Ba­sic Re­search Pro­gram.

Pro­fes­sor Ha­sunuma’s re­search team aimed to find the re­ac­tion that acts as the bot­tle­neck in the meta­bolic path­way when CO is con­verted into suc­ci­nate, and

2 then use ge­netic engi­neer­ing to speed up this bot­tle­neck re­ac­tion and in­crease the pro­duc­tion of suc­ci­nate.

The team has man­aged to raise the pro­duc­tion rate of suc­ci­nate to 7.5 times higher than pre­vi­ous stud­ies.

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