Be­ware of tablet split­ting

Health & Nutrition - - READERS’ PULSE -

Tablet-split­ting is com­mon, and is done for a num­ber of rea­sons: To in­crease dose flex­i­bil­ity, to make tablets eas­ier to swal­low and to save money for pa­tients. But split tablets could have se­ri­ous clin­i­cal con­se­quences with drugs that have a nar­row mar­gin be­tween ther­a­peu­tic and toxic doses.

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