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Health & Nutrition - - CONTENTS -

Work­ing night shifts can dam­age a per­son’s DNA, in­creas­ing the risk of can­cer as well as car­dio­vas­cu­lar, meta­bolic and neu­rode­gen­er­a­tive dis­ease, a study has found. Re­searchers found that on-call doc­tors who were re­quired to work overnight on-site had lower DNA re­pair gene ex­pres­sion and more DNA breaks than those who did not work overnight.

In these overnight on-site call doc­tors, DNA re­pair gene ex­pres­sion de­creased and DNA breaks in­creased af­ter sleep de­pri­va­tion. Dam­aged DNA in­creased af­ter only one night of sleep de­pri­va­tion. This DNA dam­age may help ex­plain the in­creased risk for can­cer and car­dio­vas­cu­lar, meta­bolic and neu­rode­gen­er­a­tive dis­eases as­so­ci­ated with sleep de­pri­va­tion, re­searchers said.

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