Ox­ford trial moves into next phase

Hindustan Times (Delhi) - - Front Page - Pra­sun Son­walkar let­ters@hin­dus­tan­times.com

nLONDON: Days af­ter re­ports sug­gested that a promis­ing coro­n­avirus dis­ease (Covid-19) vac­cine be­ing de­vel­oped by the Ox­ford Vac­cine Group showed lim­ited suc­cess on mon­keys but could fail to prevent trans­mis­sion of the virus, the de­vel­op­ers of the vac­cine at the Univer­sity of Ox­ford de­scribed their ef­forts as pro­gress­ing “very well”, mov­ing to the next phase af­ter com­plet­ing 1,000 im­mu­ni­sa­tions by its can­di­date-vac­cine on healthy hu­man adults.

The hu­man tri­als were first ini­ti­ated in April. The next phase, the sec­ond in the typ­i­cal three phases of tri­als that a vac­cine goes through, in­volves en­rolling up to 10,260 adults and chil­dren to as­sess the im­mune re­sponse to the vac­cine in peo­ple of dif­fer­ent ages and as­sess if there is a vari­a­tion.

The Ox­ford study is merg­ing Phases II and III for a speed­ier de­vel­op­ment. Phase III in­volves as­sess­ing how the vac­cine works in a large num­ber of peo­ple over the age of 18, and how well it pre­vents peo­ple from be­com­ing in­fected and

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