Hindustan Times (Delhi)

To deal with China, understand it better

The crisis has shown the lack of domain knowledge within India. Invest in it

- Anurag Agrawal is director, Institute of Genomics and Integrativ­e Biology (Council of Scientific and Industrial Research) The views expressed are personal RK Pachnanda is a retired director general, Indo-tibetan Border Police The views expressed are perso

There is now no doubt that China will remain India’s greatest strategic threat in the decades to come. Beijing is not just interested in taking control of strategic areas or in stopping India’s infrastruc­ture build-up at the border. As is visible in the statements emerging from retired officials and its State-controlled media, China wants to send a message to India — to accept Chinese dominance in the Asian hierarchy of power, stop deepening the partnershi­p with the United States, and reconcile to a curtailed global role.

New Delhi cannot do this, for its own national interests are at stake. While there is a need for a diplomatic reset, enhanced military capabiliti­es and economic policies to reduce dependence on China, one other area which requires greater investment is the expertise on China in India. India is too dependent on a very limited set of retired diplomats and military officials who have engaged with China, select intelligen­ce officials and diplomats who speak Mandarin, and a small set of academics outside government. This is not tenable. To understand Chinese motivation­s better, India needs more experts on the decision-making apparatus in China, the functionin­g of the Chinese Communist Party, the dynamic between the party and the People’s Liberation Army, China’s economic drivers and changing social dynamics, and its quest for digital dominance. For this, India must invest in language training, field visits, fellowship­s, and dedicated institutes. To battle China, understand it better.

As the cases of Covid-19 increase, many are wondering what they can do if they or someone close to them gets the infection. First, some reassuranc­e. A vast majority of those infected with SARS-COV2 is asymptomat­ic or have minimal symptoms which require no treatment. This proportion is highest among the young, more than 90% in children and young adults, but is less in older adults with co-morbiditie­s such as diabetes and hypertensi­on. In seropreval­ence studies, where we look for the presence of antibodies in people’s blood, indicating they have been infected and are recovering or have recovered, most who test positive do not recall any unusual symptoms. This indicates widespread asymptomat­ic or minimally symptomati­c infection and recovery.

While this is good at a population level and should reduce the panic associated with Covid-19, the more symptomati­c patients should not think of this as just another flu. In this group, especially for the elderly or those having diabetes, hypertensi­on or other co-morbiditie­s, there is a small but real risk of severe illness which could be fatal.

What are the available treatments for those with moderate to severe disease and when or to whom should they be administer­ed? The answers are still evolving. The treatment can be broken down into three categories. First, general supportive care targeted at managing the symptoms and general complicati­ons. Second, antiviral treatment directed at killing or limiting the growth of the virus. Third, modulating the immune response of the infected person such that it is strong enough to clear the virus, but not so much that it kills the host.

The first category, access to good quality supportive care, is simple in concept but needs a strong public health focus. There must be timely testing so that people are diagnosed early, with simple monitoring for common danger signals such as low oxygen levels in the blood that can be monitored by a simple pulse oximeter. If this is done, patients likely to become more ill can get necessary care in time — oxygen supplement­ation, with face down positionin­g (proning) and ventilator support, if needed, preferably non-invasive. Attention can also be paid to preventing, detecting and treating blood clots.

The second category is antiviral treatment. This ranges from true antiviral drugs, such as favipiravi­r and remdesivir, to commonly available medicines that may additional­ly reduce viral entry or replicatio­n such as zinc, vitamin C, chloroquin­e/hydroxychl­oroquine, azithromyc­in, doxycyclin­e, ivermectin, niclosamid­e, ciclesonid­e and indomethac­in. There is no authentic evidence that any of these are effective, but data so far offers some hope. Remdesivir seemed to accelerate recovery in one randomised controlled trial (RCT). In moderately ill patients, it may reduce death. Favipiravi­r is cheaper, has fewer side effects, and can be given orally, making it more attractive but lacks any quality RCT data and is thus used for mild to moderate illness only. Zinc and vitamin C are being commonly used by patients with mild illness, due to lack of any known or postulated side effects, with some observatio­nal data of zinc being potentiall­y useful. Treatment with chloroquin­e or hydroxychl­oroquine has not been very promising so far. While recent reports of high toxicity turned out to be false, side effects may occur at high doses, especially in those with existing heart disease.

The last category, immune modulation, looks promising since much of the severe disease is either due to uncontroll­ed viral infection in people with compromise­d immunity, or due to an exaggerate­d immune response causing damage to the lungs and other tissues.

Increasing natural immunity through vaccines appears distant at the moment and externally providing antibodies via the plasma of recovered patients (plasma therapy) is neither risk-free, nor easy to do at scale. The only published RCT for plasma therapy was inconclusi­ve. In fact, the first clear winner in immune modulation is the widely available and cheap steroid, dexamethas­one. It is expected that when used correctly, steroids will dampen excessive immune response, limit damage, and promote recovery. However, it also suppresses immunity and should not be used early in the disease. More sophistica­ted immune modulators like tocilizuma­b that can selectivel­y block cytokine storms, without compromisi­ng immunity, have also shown promising results. Many other approaches have been suggested for immune modulation, ranging from mycobacter­ium w vaccine to traditiona­l remedies that boost immunity. What works remains to be seen.

Currently, we have both a shortage of proven treatments and an excess of unproven ones. With exaggerate­d claims from every quarter, it is difficult to subjective­ly determine the best treatment. Objectivel­y, uncomplica­ted disease in otherwise healthy subjects usually requires no specific treatment beyond general support. In fact, such support is probably both necessary and sufficient to prevent most Covid-19 deaths. More specific treatment, including new antivirals and targeted immune modulators, will certainly be beneficial in specific settings but are not required for everyone. We should treat based on what we have learnt and keep learning as we treat. For this, patients, doctors and researcher­s must come together and share informatio­n at covbase.igib.res.in, a site meant for this specific collaborat­ive purpose.

Prime Minister (PM) Narendra Modi recently stated that 20 jawans were martyred but not before they taught a lesson to those who had dared to raise an eye towards

Mata”. PM assured the nation that, today, it has the capability that no one could eye even an inch of its territory. He suggested that the infrastruc­ture in the border areas had improved greatly, leading to heightened patrolling and close monitoring of movements at the border. PM also made it clear that India would respond firmly to any attempts to transgress the Line of Actual Control (LAC).

China has always made a creeping annexation part of its policy towards India. The Congress, when in power, turned a blind eye to the encroachme­nt on India’s territorie­s by the Chinese through continuous transgress­ions and border violations. Though the country entered into as many as six bilateral agreements in 1988, 1993, 1996, 2005, 2012 and 2013, it did not address the dispute over LAC. When the Chinese intruded and pitched tents deep inside India’s territory at Depsang, in 2013, the then Prime Minister Manmohan Singh merely spoke in Parliament about the Chinese having a different perception about LAC. Confidence-building Measures (CBMS) were misused by the Chinese to resort to psychologi­cal warfare and “salami slicing”. This is because, after 1962, defence forces were neglected and infrastruc­ture was shoddy.

After Modi assumed power, strengthen­ing infrastruc­ture became a national priority. Today, there has been a great leap in infrastruc­ture developmen­t at the Indo-china border on the Indian side which has served as a deterrent to China. Had the infrastruc­tural developmen­t started in past regimes, India would have been in a more dominant position today. After 2014, India created a strong road network through the Border Roads Organisati­on and the Central Public Works Department despite the small window, during the year, for constructi­on, due to the harsh winter. The Border Area Developmen­t Programme (BADP) has been allocated ~784 crore in the fiscal year 20202021. BADP stipulates that “10% of the total allocated funds will be additional­ly allocated to the states/union territorie­s abutting Indo-china Border (Arunachal Pradesh, Himachal Pradesh, Ladakh, Sikkim and Uttarakhan­d) for taking up works in the districts abutting Indo-china border”. The creation of infrastruc­ture “would help integrate these area with the hinterland, create a positive perception of care by the country and encourage the people to stay or in the border areas leading to safe and secure border” as per the ministry of home affairs.

Infrastruc­ture has developed on all borders through the comprehens­ive Integrated Border Management Systems — be it border out posts, border fencing, mobile towers, the use of technology at the border and lighting. On the Indo-tibet border, roads, helipads, tunnels and bridges have been built.

At the same time, there has been an increase in patrolling — be it long-range patrols, short-range patrols or joint patrols by the Army and the Indo-tibetan Border Police. India has held its ground in several face-offs. Regular patrols also enable us to assess China’s activities, identify features of tactical importance, dominate infiltrati­on routes, corroborat­e inputs and assert our presence. Post-2014, our patrols have been actively engaging, confrontin­g and preventing any incursions. We have not allowed any constructi­on activity in our territory within LAC. In Doklam, India stalled the constructi­on of a road by the Chinese, which would have adversely affected the nation’s strategic interests. It is only after this that China became more wary of India’s diplomatic and military might.

Work on a link road, part of an infrastruc­ture project of a strategic road in Ladakh, is one of the factors which seems to have pushed China into its misadventu­re on June 15. They were given a bloody nose by Indian soldiers. Another reason which could have irked China is the fact that India did not support the Belt and Road Initiative (BRI), which was not advisable from the country’s security point of view. BRI was to establish China’s dominance in global trade. This included the China-pakistan Economic Corridor, which is not acceptable to India as it goes through Pakistan-occupied Kashmir. Other factors which angered China could have been the friendly relations between India and the United States and the formation of the two Union territorie­s of Jammu and Kashmir and Ladakh as well as the abrogation of Article 370. This reflects China’s vulnerabil­ity and the Galwan Valley aggression seems to be the desperate act of a frustrated country.

PM Modi’s policy towards China has been a judicious mix of diplomatic, military and economic options. He and President Xi Jinping have had as many as 18 summit meetings over the past six years, including two informal meetings at Mamallapur­am and Wuhan. Several meetings have been held at different levels. The 15th meeting of the Working Mechanism for Consultati­on and Coordinati­on, was held on June 24, where India stressed on respecting LAC and both sides agreed to expeditiou­sly implement the understand­ing on disengagem­ent and de-escalation.

While diplomatic parleys should continue, it is imperative to continue the PM’S policy to strengthen both the nation’s infrastruc­tural and military build-up to contain the Dragon if it challenges us again. No one can challenge a determined India. Though India is a peaceful nation, we will negotiate only from a position of strength. And this can happen when strong leadership under PM Modi is guiding India’s security policy based on national interests.

 ?? HT PHOTO ?? With exaggerate­d claims, it is difficult to n determine the best treatment
HT PHOTO With exaggerate­d claims, it is difficult to n determine the best treatment

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