Hindustan Times (Delhi)

RML testing 4 technologi­es by Israel to detect Covid-19 faster

- Anonna Dutt anonna.dutt@htlive.com

nNEW DELHI: Four technologi­es to detect coronaviru­s disease (Covid-19) in 30 seconds developed by scientists from Israel are being evaluated at Delhi’s Dr Ram Manohar Lohia hospital.

About 10,000 people will be tested twice; once using the gold standard molecular RT-PCR test and then the four Israeli technologi­es to evaluate whether these innovation­s will work in a field setting.

Unlike the swab sample collection method, for this test, people will have to blow into or speak in front of a breathalys­er sort of an instrument which will collect a sample for testing.

If successful, these technologi­es can pave the way for the safe opening of businesses and people will be able to coexist with the virus till a vaccine is developed, researcher­s said.

“The diagnostic­s are being tested in a collaborat­ion between the Israeli Defence R&D, the Defence Research and Developmen­t Organisati­on (DRDO), and

Council of Scientific and Industrial Research (CSIR). The first technology attempts to detect the virus by a technique called terahertz spectrosco­py. In this, a sample is taken, deposited on a chip and then examined in a manner that specifical­ly detects SARSCOV-2 virus that causes Covid-19. This does not involve any chemistry or reagents as it does in the current standard tests. The results will come in less than a minute,” said professor K Vijay Raghavan, principal scientific advisor to Prime Minister Narendra Modi.

Raghavan said the second approach is called an isothermal test, and it amplifies the genetic material of the virus rapidly.

“The third approach detects what are called poly amino acids specific to the virus. The fourth approach is to study speech samples from asymptomat­ic and presymptom­atic patients, compare them with others and see if the tools of artificial intelligen­ce can be used to identify those who are Covid-19 positive. All these approaches are working well in the laboratory setting, but the challenge is to see how they will work in a field setting,” he said.

The final product can be a combinatio­n of two or more technologi­es as well. “We will see which of the four technologi­es works better at detecting Covid-19 afflicted people. It could be a combinatio­n of two of these technologi­es as well. We hope to see a very robust diagnostic test finally,” said Israeli ambassador to India Ron Malka.

India’s manufactur­ing capacity, the ambassador said, made India a natural fit for these trials. “We are a small country and do not have the manufactur­ing capability like India. By combining advanced Israeli and Indian technology and India’s manufactur­ing prowess, we can find a way to resume our lives and exist alongside the virus till a vaccine is developed,” he said.

Prof Raghavan said, “What was yesterday considered esoteric research in now being tested for implementa­tion. Science is about such rigorous tests. If the technologi­es pass the test, the collaborat­ors will roll them out in India and elsewhere.”

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