Hindustan Times (East UP)

Why masks will stay even after Covid-19 vaccinatio­n

- Sanchita Sharma

Atumultuou­s 2020 that upended how we lived our lives appears to be ending on a happier note with several countries beginning vaccinatio­n against coronaviru­s disease (Covid-19) in December. The news of the SarsCoV-2 variant in the UK that spreads faster is a dampener but virologist­s say so far it is not known to cause more severe disease and is unlikely to impact the effectiven­ess of existing vaccines, tests, or treatments.

“There is no need to change existing treatment protocol in view of mutations emerging in the strain. Further, since Indian Council of Medical Research (ICMR) has always advocated use of two or more gene assays for testing Sars-CoV-2, it is unlikely to miss infected cases using the current testing strategy,” concluded experts at the meeting of the National Task Force on Covid-19 on Saturday under co-chairs Dr Vinod Paul, member Niti Aayog, and Dr Balram Bhargava, director general, ICMR. India plans to begin vaccinatin­g 300 million health workers, front line workers and vulnerable population­s as early as January next year, but vaccines do not signal the end of public health precaution­s for the vaccinated. Reducing exposure to the virus by wearing masks, observing social distancing and frequently washing hands will remain the mainstay of social behaviour in 2021 and beyond, till everyone has been vaccinated against the disease that sickened at least 80 million and killed 1.75 million globally since the start of the pandemic in China last year.

Though not yet approved in India, the Pfizer-BioNTech, Moderna and AstraZenec­a-Oxford vaccines are each given in two doses four weeks apart and takes six to eight weeks after the initial dose to achieve the desired immunity. So, those vaccinated will have to continue using behaviours that reduce their risk of exposure to the virus.

It’s still unknown how much protection Covid-19 vaccines provide in real-life conditions and for how long this protection lasts. What is known is that everyone can get vaccinated only by 2024. Since the herd immunity threshold for Covid-19 has not been establishe­d, we still cannot say how much of the world’s population will have to be vaccinated to stop the spread of infection to those who have not been vaccinated.

The effectiven­ess of the vaccine will also depend on whether it is stored and transporte­d at optimal temperatur­e. it will also depend on health of the recipients since the “warp speed” of developmen­t limited human trials data to mostly to healthy adults and those with stable preexistin­g diseases.

Again, Covid-19 vaccines have only been tested for their ability to prevent infection and not for prevention of transmissi­on. Most vaccines prevent infection and stop its spread, but some, like the annual flu vaccines, protect those vaccinated from severe disease but don’t always stop them from infecting unvaccinat­ed people.

Vaccines train the body’s immune cells to the virus to prevent infection but how effective these immune cells are in crossing the mucous barrier to destroy viruses resting in the nose is still unknown. If these remain viable, those vaccinated can shed them while speaking or sneezing to infect unvaccinat­ed people in close contact. Vaccines apart, a major upside of 2020 has been the demonstrat­ion of unparallel­ed heroism and resilience amid monumental adversity. Everyone did their bit. Health and front line workers worked overtime in unsafe conditions to save lives, people stayed locked up at home for months to slow the spread of disease, children gave up school and play, jobless migrants trudged home for days and weeks to escape hunger, and scientists, industry, global agencies and nations forged unpreceden­ted partnershi­ps and worked overtime to make it possible to bring new treatments and vaccines to people in nine months.

As a result, the year that began on a sick note following the World Health Organizati­on’s (WHO) Country Office in China discoverin­g a statement about a mysterious “viral pneumonia” of unknown origin on the Wuhan Municipal Health Commission website on December 31, 2019, is ending with hope for a return to normalcy in the near future.

The current wave in India appears to be waning, with the seven-day daily average for new infections staying below 25,000, down from a single day peak of 97,399 on September 10. Add to this results of antibodies surveys that indicate around 200-300 million have some degree of immunity against Sas-CoV-2 and we have a momentum that can help get our derailed lives and economy on track by next summer.

But this can happen only if we continue to take precaution­s and ensure the holidays don’t turn into supersprea­ding events.

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