Hindustan Times (East UP)

What we know about Omicron variant so far

- Binayak Dasgupta letters@hindustant­imes.com

NEW DELHI: Omicron seems to spread far quicker than any other variant of Sars-Cov-2, show new estimates from the United Kingdom, the first nation other than South Africa from where such data has become available.

In the UK, the variant has estimated doubling time of infections of 2.2 days, lower than the 3 days in South Africa at present, according to an analysis by epidemiolo­gist Trevor Bedford at the Fred Hutch Cancer Research Center in Seattle, US. In England alone, the variant is likely to lead to 60,000 cases a day by Christmas, the Guardian newspaper reported, citing epidemiolo­gist John Edmunds at the London School of Hygiene and Tropical Medicine.

According to Bedford’s calculatio­ns, detailed on Twitter on Friday, an infected person in South Africa is passing it on to three or four people on average. In the UK, this number is six.

To put it into contrast, the virus first seen in Wuhan, when social distancing, wearing masks and vaccines were not widespread, the number of secondary infections – calculated as the R number – was between 2-3. This suggests there is a high possibilit­y that Omicron will lead to a new wave of cases wherever it takes hold.

The implicatio­n of this was summed up by an evidence paper released by the Scotland on Friday, which too found the doubling time in the region to be 2.3 days.

“Omicron is spreading at a rate that threatens a rapid and large surge of Covid-19 cases. Even if the resulting illness is relatively mild the number of cases could potentiall­y cause great disruption... as more people would be absent from work due to illness and asked to isolate” the paper said.

Implicatio­n for India

Does Scotland’s assessment­s hold true for India as well? Of late, experts and government authoritie­s have cited sero-surveillan­ce and vaccinatio­n data to contend that the country has a vast population of people either exposed or vaccinated (or both).

A vaccine or a past infection significan­tly minimises the likelihood of severe disease, but how true that holds in the Indian context is still unknown. Omicron is significan­tly resistant to antibodies from either, studies published in the past week showed; India’s vaccines do not compare on the same parameters as the mRNA jabs used in the West; and much of the Global North right now is entering its peak holiday season, which creates ideal conditions for supersprea­der events.

But India still has significan­t reasons to be concerned.

“The variant has me worried. With Omicron, the rules have changed. With the UK data, the super-spreading events, and the spread in South Africa, the rise of cases is fairly serious…” said Ashoka University professor of physics and biology, Gautam Menon, during a webinar on Friday. “It’s very hard to tell if there will be significan­t pressure in hospitalis­ations and ICUs, but India is a large country... Even if 0.1% or 0.05% of the unvaccinat­ed end up in hospitals, it will be a large number.”

Shahid Jameel, noted virologist and the former head of India’s virus genome sequencing group, said, “the more cases, the more people we will see in hospitals” as he urged officials to ensure hospital capacity is adequate.

Whether Omicron leads to milder disease is not clear yet, but that it is more resistant has been establishe­d, and evidence is now mounting that it could surpass Delta’s explosive transmissi­bility.

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