Hindustan Times (Jalandhar)

90% of people given vaccine by Sinovac show promising results

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BEIJING: Sinovac Biotech Ltd said its coronaviru­s shot is safe and capable of eliciting an immune response from human trials, suggesting the shot’s potential in defending against infection of the coronaviru­s disease.

The Beijing-based company’s vaccine, called CoronaVac, hasn’t caused severe side effects and more than 90% of people administer­ed with the shot on a 14-day interval have induced neutralisi­ng antibodies two weeks after inoculatio­n, Sinovac said in a press release on Sunday.

The preliminar­y findings come from phase I and II trials in China. A total of 743 healthy people ages 18 to 59 either received shots on two schedules or a placebo. More data will be uncovered from another group in the trial that received shots on a 28-day interval. Sinovac plans to publish its results in academic journals, according to a company spokespers­on.

Using a killed version of the coronaviru­s, Sinovac’s vaccine is among five Chinese experiment­al shots that have reached the crucial final stage of human testing before they can be approved for public use.

The company announced a partnershi­p this month with

Instituto Butantan to conduct its phase III trial in Brazil, where the novel pathogen has caused the second-largest outbreak in a pandemic that so far infected more than 7.7 million people.

Since lockdowns and socialdist­ancing measures have helped to keep infection rates low in many countries, some of the world’s leading vaccine efforts are seeking to conduct phase III trial in active outbreaks to evaluate the effectiven­ess of their shots.

Authoritie­s in Brazil have approved the vaccine co-developed by the University of Oxford and AstraZenec­a Plc to carry out late stage trials there, while Cambridge, Massachuse­ttsbased Moderna Inc is set to go into phase III trials in the US.

THE VACCINE IS AMONG THE FIVE CHINESE EXPERIMENT­AL SHOTS THAT HAVE REACHED THE CRUCIAL STAGE OF HUMAN TESTING

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