Hindustan Times (Jammu)

What we know about Omicron variant so far

- Binayak Dasgupta binayak.dasgupta@htlive.com

The big questions -whether the newest variant of concern (VOC) is more transmissi­ble, more resistant to vaccine or past infection immunity, or more virulent – are likely to take some time to be answered. To determine these, experts will need to wait for adequate epidemiolo­gical and clinical data. At the least, cases need to be watched for three weeks, the time by when infections usually completely resolve or take a turn for the worse.

For now, there are only two approximat­e knowns with the Omicron variant: first, it is almost certainly out-competing the Delta variant; and second, evolutiona­rily, it has taken a much farther leap than variants typically have.

Late on Wednesday, the Network for Genomic Surveillan­ce in

South Africa (NGS-SA) released new details about their surveillan­ce of Sars-Cov-2 variants, including findings specific to Omicron that they first sequenced in a sample collected on November 8.

Much still remains unknown about the variant of concern ( VOC), but the new report strengthen­s one of the earliest assumption­s: Omicron is likely displacing Delta, the VOC that led to India’s devastatin­g summer surge and is at present triggering hot spots of outbreak in much of Europe.

From no sequences in October, Omicron accounted for 74% of the 249 genotyped samples by NGS-SA. In the same period, Delta prevalence plummeted from 83% to 22% of the samples.

The switch is almost identical to what happened in May and June, when the then prevalent variant, Beta, dropped from being found in 65% of the samples to 18% in a span of 30 days, while Delta accounted for 66%, after being found in 16% of samples in the month before.

Delta went on to displace Beta and trigger a new wave in South Africa, and it appears Omicron is on a similar course. Overall, South Africa’s case numbers doubled daily for last two days.

 ?? FILE ?? From no sequences in October, Omicron accounted for 74% of the 249 genotyped samples by NGS-SA.
FILE From no sequences in October, Omicron accounted for 74% of the 249 genotyped samples by NGS-SA.

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