Hindustan Times ST (Mumbai)

Cyclone-30 becomes operationa­l; cancer diagnosis to improve

- Snehal Fernandes

MUMBAI: The country’s biggest cyclotron facility that will produce radioisoto­pes vital for diagnosis and treatment of cancer became operationa­l last week. The machine – Cyclone-30 — is housed at the Kolkata-based Variable Energy Cyclotron Centre (VECC) under the Department of Atomic Energy (DAE) and will start regular production by midnext year after supporting nuclear systems are commission­ed and regulatory clearances are obtained.

“With increasing number of Indians diagnosed with cancer every year, the cyclotron machine will produce radioisoto­pes for nuclear imaging specifical­ly for cancer detection,” said Amitava Roy, director, VECC. “Our cyclotron has high productivi­ty, and therefore will cater to many patients.”

A new study in the Lancet Global Health released last week found that 8.3% of the total number of deaths in India in 2016 was because of cancer, and the number of new cases has increased from 5.48 lakh in 1990 to 1.1 million in 2016.

At present, many radioisoto­pes are imported while some are produced in nuclear research reactors such as the Apsara at the Bhabha Atomic Research Centre (BARC), and remaining in cyclotrons facilities run by large private hospitals. For instance, the country imports radioisoto­pes Germanium-68/gallium-68 that accurately diagnoses breast cancer, and Palladium-103 to detect and treat prostate cancer. The addition of Cyclone-30, said Roy, will increase the availabili­ty of radioisoto­pes and bring down the

cost of treatment. “This high-energy and high-yielding machine will bring down imports, while raising the possibilit­y of exporting radioisoto­pes in the future.”

For the first time last week, the cyclotron became operationa­l when 30 MEV (million electron volt) beam reached the Faraday Cup – a metal cup designed to catch charged particles in vacuum. The beam was used to produce Fluorine-18 isotope to prepare radiopharm­aceutical Fluorodeox­yglucose used by the Board of Radiation and Isotope Technology (BARC) to diagnose various types of cancers. VECC also plans to install iodine-123 isotope facility for thyroid imaging and detecting thyroid cancer.

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