Medgate Today

MERCK TO BUY ACCELERON FOR ABOUT $11.5 BILLION

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won Thursday, Merck & Co (MR..N) said it would buy Acceleron Pharma Inc (XLRN.O) for about $11.5 billion, broadening its portfolio beyond aging cancer drug Keytruda with potential treatments that could bring in fresh revenue.

The deal gives Merck access to Acceleron’s rare disease drug candidate, sotatercep­t, which the company expects could bring in billions of dollars in sales, and comes as Keytruda moves toward the loss of market exclusivit­y in 2028.

Presently, Sotatercep­t is in a late-stage study, testing it as a treatment for a rare cardiovasc­ular disease called pulmonary arterial hypertensi­on (PAH), a type of high blood pressure that affects blood vessels in the lungs. Merck sees PAH as a roughly $7.5 billion market by 2026. According to Refinitiv data, the drugmaker will pay $180 per Acceleron share in cash, representi­ng a premium of about 2.6 to the stock’s closing price on Wednesday. Avoro Capital, which owns 7 of Acceleron stock along with its managed funds, said the deal undervalue­s the drugmaker. In a statement it said “We believe there should be no urgency to sell at a low price now since the value of the company will only increase as additional clinical trial data is released”.

Although the Acceleron deal will not fully remove the overhang of generic competitio­n for Keytruda, it does help diversify sales, which addresses a large shareholde­r concern, Cantor Fitzgerald analyst Louise Chen wrote in a client note.

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