An ac­cu­rate test to de­tect ge­netic ab­nor­mal­i­ties

Mother & Baby - - WHAT’S ON -

LIFECELL, In­dia’s premier mother and baby di­ag­nos­tics com­pany and stem cell bank, launched “Pen­tas­tic”an ul­tra­sound and bio­chem­istry-based blood test un­der­taken in the first trimester of preg­nancy be­tween 11 to 13 weeks to screen for ge­netic ab­nor­mal­i­ties, struc­tural mal­for­ma­tions in the foe­tus, and se­ri­ous high blood pres­sure in preg­nancy. Com­pared to con­ven­tional screening tests that use only two an­a­lytes, the new Pen­tas­tic test in­cor­po­rates five an­a­lytes to pre­dict the risk. Ad­di­tion of these new an­a­lytes can sig­nif­i­cantly im­prove the de­tec­tion of these ab­nor­mal­i­ties whilst si­mul­ta­ne­ously low­er­ing the num­ber of false alarms raised. This would lead to sub­stan­tial im­prove­ments in health out­comes whilst pro­vid­ing a higher level of re­as­sur­ance for expectant par­ents. An­other sig­nif­i­cant ad­van­tage of the Pen­tas­tic test is that it helps in de­tect­ing pre-eclamp­sia in the first trimester. This is a med­i­cal con­di­tion that in­creases the risk both for mother and the baby dur­ing preg­nancy. Con­ven­tional bio­chem­i­cal screening and even ad­vanced DNA-based tests such as NIPT do not help in iden­ti­fy­ing this con­di­tion.

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