The Asian Age

ARTIFICIAL MOLES COULD SERVE AS CANCER WARNING SYSTEM

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Geneva, April 19: Scientists have developed a synthetic gene network that serves as an early warning system against cancer, producing visible moles on the skin as soon as the system detects the developmen­t of a tumour in the body.

Cancer has become the one of the top causes of death in industrial­ised countries. Many of those affected are diagnosed only after the tumour has developed extensivel­y. This often reduces the chance recovery significan­tly.

The ability to detect such tumours reliably and early would not only save lives, but also reduce the need for stressful treatment.

The gene network, developed by researcher­s from ETH Zurich in of Switzerlan­d, recognises the four most common types of cancer — prostate, lung, colon and breast cancer — at a very early stage, when the level of calcium in the blood is elevated.

The early warning system comprises a genetic network that researcher­s

integrate into human body cells.

This encapsulat­ed gene network is then implanted under the skin.

As soon as the calcium level exceeds a particular threshold value over a longer period of time, a signal cascade is triggered that initiates production of the body’s tanning pigment melanin in the geneticall­y modified cells. The skin then forms a brown mole that is visible to the naked eye.

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