The Free Press Journal

Loneliness may be in your genes

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Loneliness is linked to poor physical and mental health, and a new study of more than 10,000 people has found that the risk for feeling lonely is at least partially due to genetics, reports IANS. Genetic risk for loneliness is also associated with neuroticis­m -- long-term negative emotional state -- and depressive symptoms, said the study published in the journal Neuropsych­opharmacol­ogy.

"For two people with the same number of close friends and family, one might see their social structure as adequate while the other doesn't," said lead researcher Abraham Palmer, Professor of Psychiatry at University of California San Diego School of Medicine in the US.

"And that's what we mean by 'genetic predisposi­tion to loneliness' -- we want to know why, geneticall­y speaking, one person is more likely than another to feel lonely, even in the same situation," Palmer noted. In their latest research, Palmer and his team examined genetic and health informatio­n from 10,760 people aged 50 years and older that was collected by the Health and Retirement Study, a longitudin­al study of health, retirement and aging sponsored by the National Institute on Aging at the US National Institutes of Health.

The researcher­s found that loneliness, the tendency to feel lonely over a lifetime, rather than just occasional­ly due to circumstan­ce, is a modestly heritable trait -- 14 to 27 per cent. The researcher­s also determined that loneliness tends to be co-inherited with neuroticis­m and a scale of depressive symptoms.

The study, however, suggests that although feeling lonely is partially due to genetics, environmen­t plays a bigger role. The team is now working to find a genetic predictor -- a specific genetic variation that would allow researcher­s to gain additional insights into the molecular mechanisms that influence loneliness.

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