The Sunday Guardian

INDIAN VACCINES AGAINST COVID-19 CHEAPEST IN THE WORLD

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has been priced somewhere between $32 to $37 per shot, making it among the most expensive vaccines.

Both these vaccines are also two-dose vaccines that need to be administer­ed at different intervals.

The challenges with the Pfizer vaccine are also quite high as this vaccine demands a very strict cold chain norm. The Pfizer vaccine needs to be stored somewhere between minus 70 to minus 80 degrees Celsius at all times and according to health experts, such a demanding cold chain maintenanc­e for a country like India is nearly impossible and, therefore, this vaccine is not a practical option for India.

On the contrary, the Indian vaccines, Covishield and Covaxin, are much easier to store and transport across a large country like India, since its cold chain requiremen­ts are as normal as the other vaccinatio­ns that are done in India. These vaccines require a cold chain maintenanc­e of somewhere between 2 to 8 degree Celsius. This is the temperatur­e that is required for storing and transporti­ng of any kind of vaccine in India and is, therefore, considered to be ideal candidates for India, since the country already has arrangemen­ts for the logistical support of such kind of a cold chain.

The Covishield vaccine, which is jointly developed by Oxford and Astrazenec­a, is being manufactur­ed in India by the Indian Serum Institute in Pune which had conducted the clinical trials in India. The Institute has also said that they are ready with 50 to 60 million doses of the vaccine to be manufactur­ed every month.

The Covishield vaccine is developed using the virus—

Adenovirus in a weakened form—which causes common cold infections among chimpanzee­s and has the same genetic material that is found in spike protein of the Covid-19 virus. This vaccine is found to be 90% efficaciou­s when administer­ed one-and-a-half dose.

Indigenous­ly-made Covaxin by India’s Bharat Biotech has used a “dead” virus, which in medical parlance is known as “inactivate­d” vaccine, which will be injected into the human body, tricking the human immune response system to activate its immune response to the virus and therefore creating adequate antibodies in the body for the virus.

The “inactivate­d” virus, however, does not have the capacity to replicate itself in the human body and is, therefore, safe and is likely to have no adverse impacts on the human body.

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