Irish Independent

Who will be tested for antibodies – and are we going to get immunity passports?

- Eilish O’Regan

Q. The health service is to start testing people next month for antibodies to see if they have had the coronaviru­s. Will that result in people with antibodies getting immunity passports? A. No. Screening involves a blood test for antibodies to find who has had the coronaviru­s and recovered.

Two or three weeks after the infection takes place, the immune system builds antibody responses against the virus, which can be detected by a lab test. The aim is to get a better measure of the true rate of infection here.

The idea of immunity passports – certificat­es people would get on the assumption they would be immune to reinfectio­n – was first mooted in Germany.

But that seems to have been parked for now because it is too early to say if someone is protected against reinfectio­n.

Q. Will these blood tests be made available to everyone? A. They will be directed at a few thousand people at first, from a county with high prevalence and one with low prevalence which are representa­tive of the wider population in categories such as age and gender.

There are more than 23,400 laboratory confirmed cases of the virus here to date but the real numbers of people infected are likely to be higher. Prof Philip Nolan of Maynooth University estimates it could be slightly more than double that figure.

Q. Other countries are also doing this antibody testing. What have they found?

A. Results from antibody tests in Gangelt, in the Heinsberg district of Germany, suggest the outbreak is much greater than official figures show.

The preliminar­y results suggest 15pc of Gangelt, with a population of 13,000, had the virus at some stage. Antibody testing in New York city, which was badly hit, suggested the true rate of infection was as high as 21.2pc. Some 17pc of people in London and 5pc of the population in the rest of England tested positive for coronaviru­s antibodies, UK Health Secretary Matt Hancock said yesterday.

Some scientists here have speculated around 6pc of the population may have had the infection because so many had little or no symptoms.

Q. When will people who have developed antibodies know if they are protected from reinfectio­n?

A. There are a lot of studies under way across the world looking at this. Obviously, if a substantia­l number of the population knew they would have immunity for a year or even two it would be a major boost for healthcare staff and the wider workforce. The World Health Organisati­on (WHO), however, says there is no evidence yet that people who have recovered from coronaviru­s and have antibodies are protected against a second infection.

The WHO said relying on antibodies at this stage of the pandemic could increase the risk of spreading the virus.

The Health Protection Surveillan­ce Centre here states that a person may be immune from reinfectio­n for the first few months.

Q. Will the informatio­n which is gathered from antibody testing here be of value in exiting lockdown? A. If it is found that a high percentage of the population here has been infected, it may allow for more risks to be taken. More is learned about the virus and there may be more clarity about who is immune. New revelation­s about the virus in relation to symptoms, its transmissi­on and impact on victims emerge every week.

Q. Sweden is controvers­ially aiming for herd immunity – is it working?

A. Herd immunity involves a level of the disease of around 80pc in the population to stop the spread of the virus. It has no lockdown and it’s too early to say if it will work. The price is the highest death rate in Europe.

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