The Irish Mail on Sunday

What about those ‘risky’ sleeping pills from the GP?

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Three medication­s can be used to treat insomnia: zopiclone and zolpidem — collective­ly known as Zdrugs — and melatonin.

Z-drugs work by increasing the activity of the brain chemical gamma-aminobutyr­ic acid, which induces feelings of relaxation and sleepiness.

They were first marketed in the early 1990s as a safer option than addictive benzodiaze­pine tranquilli­sers such as temazepam.

In the short term, Z-drugs cause few problems and can be a lifeline to those battling a debilitati­ng bout of insomnia.

However it is now well recognised that they carry similar risks to the older drugs, such as dependence and withdrawal, as well as the return of sleep problems.

They can also trigger side effects, including daytime drowsiness, which can lead to traffic accidents, falls and fractures. They can also cause sleepwalki­ng.

There’s even some evidence that, if taken long-term, they could increase the risk of dementia.

The HSE’s guidance tallies with the UK’s National Institute for Health and Care Excellence (NICE) in recommendi­ng that patients should be on the lowest dose for the shortest time possible.

Professor Guy Leschziner, a London-based neurologis­t, says: ‘Zdrugs should be used for a maximum of two weeks — when people can’t sleep due to extreme stress, for example.’

Melatonin — a synthetic version of the hormone naturally produced by the body to trigger sleep — is similarly tricky.

However, Prof Leschziner says: ‘Melatonin doesn’t work for everyone and its effects can wear off. Patients don’t become dependent on it but there are questions as to whether taking it might then suppress your own normal production.

‘If you have issues with your sleep, using effective non-drug-based therapies is the way to go.’

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