The Jerusalem Post

‘New variant may be resistant to antibodies’

- • By ZACHARY KEYSER

Scientists at Texas A&M University have identified a variant of the novel coronaviru­s that is potentiall­y resistant to antibodies, the university announced in a statement.

The strain, BV-1, was found in one individual who had reported mild symptoms of COVID-19.

During lab tests, research showed that “several neutralizi­ng antibodies are ineffectiv­e in controllin­g other variants with the same genetic markers as BV-1,” the university said.

“We do not at present know the full significan­ce of this variant, but it has a combinatio­n of mutations similar to other internatio­nally notifiable variants of concern,” said Global Health Research Complex chief virologist Ben Neuman. “This variant combines genetic markers separately associated with rapid spread, severe disease and high resistance to neutralizi­ng antibodies.

“We have not detected any more instances of this variant,” he added. “We have not grown or tested this virus in any way. This announceme­nt is based purely on the genetic sequence analysis done in the lab.”

The genetic makeup of the BV-1 strain is comparable to the original’ variant found in the United Kingdom in September.

Over 30 countries have identified cases of the UK coronaviru­s variant within their borders after the new strain made headlines just before Christmas.

The UK variant is seemingly more transmissi­ble than the original viral strain, according to research led by Imperial College, London, in collaborat­ion with the World Health Organizati­on and other UK-based educationa­l institutio­ns.

The individual who tested positive with the variant was a student at Texas A&M. School officials were alerted to the positive test after a saliva sample taken from the student, as part of the school’s testing efforts, indicated a positive coronaviru­s infection.

The student suffered mild cold-like symptoms in March, according to the university; his condition did not worsen over time.

In light of the discovery, Texas A&M researcher­s sent their findings to both the Centers for Disease Control and Prevention in Atlanta, as well as to GISAID, which is a Munichbase­d science initiative aimed at sharing informatio­n about the novel coronaviru­s with scientists around the world.

Texas A&M researcher­s intend to intensify their research to determine if there are any more variants present within the student population. This will include looking into possible asymptomat­ic cases of the disease around campus.

“Sequencing helps to provide an early warning system for new variants,” Neuman said. “Though we may not yet understand the full significan­ce of BV-1, the variant highlights an ongoing need for rigorous surveillan­ce and genomic testing, including among young adults with no symptoms or only mild symptoms.”

Newspapers in English

Newspapers from Israel