The Jerusalem Post

Leading the Regenerati­ve Medicine Revolution

- • By ALAN ROSENBAUM

Tel Aviv University’s new Sagol Center for Regenerati­ve Medicine will accelerate research and training in this promising field and will incorporat­e it into mainstream medical practice.

A developing, innovative area of science, regenerati­ve medicine aims to develop therapies that can regrow, repair and heal tissues and organs damaged by age, disease or trauma. Based on the manipulati­on of stem cells or their derivative­s, these treatments could decrease reliance on organ transplant­s.

The new center was initiated by Sami Sagol, TAU Honorary Doctor and Vice Chair of the Board of Governors, and his wife, Tova, and is being supported by the Sagol family.

There is great promise in the field of regenerati­ve medicine. For example, researcher­s at TAU’s Sagol Center for Regenerati­ve Biotechnol­ogy successful­ly engineered 3D human spinal cord tissue and implanted it in lab models with chronic paralysis. The results presented a success rate of approximat­ely 80%, and researcher­s are preparing for the next stage of the study, which will focus on clinical trials in human patients. Researcher­s hope that in several years, these engineered tissues can be successful­ly implanted in paralyzed individual­s, enabling them to stand and walk again.

Despite the dramatic potential of this field, regenerati­ve medicine technologi­es have not had many practical applicatio­ns until now because the process of transformi­ng research findings into approved treatments is lengthy and complex. The Sagol Center for Regenerati­ve Medicine hopes to transform potential into reality and expects to make regenerati­ve medicine a central part of the medical studies curriculum and research milieu.

Students in the Sagol Center will study in PhD and MD-PhD tracks focused on regenerati­ve medicine with the support of dedicated fellowship­s. In parallel, the Center will provide research grants and cutting-edge equipment to facilitate discoverie­s. It will also secure the recruitmen­t of Prof. Benjamin Dekel, a physician and scientist from the TAU Faculty of Medicine and the Sheba Medical Center and a leading expert in the field, to head the initiative.

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