Jamaica Gleaner

Brains of overweight persons older than lean counterpar­ts

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A NEW study has found that the brains of overweight people are 10 years older compared with their lean counterpar­ts – but only when they reach middle age and up.

In a study published in the journal Neurobiolo­gy of Ageing, researcher­s from the Cambridge Centre for Ageing and Neuroscien­ce in the United Kingdom analysed 473 people between the ages of 20 and 87 and divided them into two categories, depending on their weight: lean and overweight. In the end, they found that overweight people had less white matter (the part that transmits informatio­n) in their brains compared with their leaner counterpar­ts.

From there, they calculated how white matter volume relates to age across the two groups. In doing so, they found that an overweight person had a white matter volume comparable to a lean person who is 10 years older than them.

The fact that we only saw these difference­s from middle age onwards raises the possibilit­y that we may be particular­ly vulnerable at this age.

VULNERABLE AGE

Interestin­gly enough, however, they only found this to be the case in people who are middle age and above, giving credence to the belief that our brains are particular­ly vulnerable during that period of ageing.

“The fact that we only saw these difference­s from middle age onwards raises the possibilit­y that we may be particular­ly vulnerable at this age,” noted senior author, Professor Paul Fletcher, in the report. “We’re living in an ageing population, with increasing levels of obesity, so it’s essential that we establish how these two factors might interact,

since the consequenc­es for health are potentiall­y serious.”

However, while researcher­s now know what obesity can do to people in those age groups, they still don’t know why that is the case.

“As our brains age, they naturally shrink in size, but it isn’t clear why people who are overweight have a greater reduction in the amount of white matter,” Dr Lisa Ronan of the Department of Psychiatry at the University of Cambridge stated. “We can only speculate on whether obesity might in some way cause these changes or whether obesity is a consequenc­e of brain changes.”

Similarly, they still don’t yet know the full implicatio­ns of these changes in brain structure.

“This must be a starting point for us to explore in more depth the effects of weight, diet and exercise on the brain and memory,” the report stated.

The study also found that despite the difference­s in the volume of white matter between lean and overweight individual­s, there was no apparent connection between being overweight or obese and an individual’s intelligen­ce or cognitive functions.

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