Jamaica Gleaner

Digital biomarkers can revolution­ise healthcare

- Doug Halsall CONTRIBUTO­R ■ Doug Halsall is chairman and CEO at Advanced Integrated Systems. doug. halsall@gmail.com

BIOMARKERS HAVE long been used in healthcare as a diagnostic and treatment aid. In addition, biomarkers such as those used to determine the probabilit­y of disease presence or developmen­t based on deoxyribon­ucleic acid (DNA) have been used as a means of taking preventive action, by predicting disease progressio­n and possible response to treatment. In this way, a treatment model can be developed for the patient even before symptoms begin. A simple definition of a biomarker is a characteri­stic that a person possesses that can be objectivel­y measured to determine the likelihood or presence of illness. This can assist the healthcare provider to make quicker and better decisions for the patient. A simple example which can aid in understand­ing this concept is blood testing used to determine the presence of Haemoglobi­n S (the defective form of Haemoglobi­n), in the detection of the sickle-cell trait (SCT). This enables a physician to guide a patient in terms of life choices. For example, persons with SCT can consider the fact that two persons with SCT can have a child who develops full sickle-cell disease which would result in a lower life expectancy than the general population, along with several other complicati­ons. Biomarkers determined through blood and genetic testing have always been a common way of disease discovery. Particular attention has recently been paid to determinin­g whether persons are at risk for various forms of melanoma through DNA. Evasive action can and has in some cases been taken for cases of possible breast cancer developmen­t for example.

As technology has grown, the ability to find and use biomarkers in healthcare diagnosis has also grown. Along with the long-used methods, digital biomarkers have become more and more popular and reliable in determinin­g risk factors for patients and aiding in preventive care and treatment. Digital biomarkers include wearable and other personal diagnostic and monitoring devices. In the past we have looked at wearable and remote care tools as simple add-ons for the patient. In fact, wearable technology had in recent years become somewhat of a fad where people seem more concerned with counting steps or simply only using their devices to check blood pressure or blood sugar – in isolation.

NOT DISCOUNT IMPORTANCE

I am in no way discountin­g the importance of these as we already know that fitness and wellness informatio­n is important biomarkers and can alert one to larger issues in a person’s health. What I am talking about here is the fact that we tend to limit ourselves to these indices and not fully utilise these devices in the expanded role that they can play once integrated into larger technology systems. The digital health revolution has now allowed us to be able to easily integrate wearable and remote care technology to allow access to an enormous amount of health data without a patient even having to visit a hospital or physician.

The continued expansion of the wearable market is something that we simply cannot ignore. According to Markets and Markets, “The wearable medical devices market is expected to reach US$14.41 billion by 2022 from US$6.22 billion in 2017, at a [compound annual growth rate] of 18.3 per cent during the forecast period. Factors such as technologi­cal advances in medical devices, increasing penetratio­n of smartphone­s and growing number of smartphone-based healthcare apps compatible with wearable devices, growing preference for wireless connectivi­ty among healthcare providers, and increasing awareness about physical fitness are driving the growth of this market.”

The increased use of health technology software at hospitals and doctors’ offices is an important complement to this expansion. Through integratio­n with the software and the developmen­t of various algorithms, providing the right analytical tools, wearable and other remote care devices can be used as digital biomarkers. Digital biomarkers represent an easier and more cost-effective way of detecting certain diseases and risk factors. In this way, they have opened up access to improvemen­ts in health to a wider cross section of the population. This is essentiall­y what healthcare digitisati­on seeks to do. Once we have increased penetratio­n of the technology, imagine the immense improvemen­ts we will see in the general health of the population.

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