UNMC, Ananda enroll 1st patient in clinical trial for PTSD
OMAHA, Neb. & GREENWOOD VILLAGE, Colo., March 14: The University of Nebraska Medical Center (UNMC) and ANANDA Scientific Inc. has announced that the first patient has been enrolled in an FDA-approved clinical trial evaluating Nantheia™ ATL5, an investigational drug using cannabidiol in ANANDA’s proprietary Liquid Structure™ delivery technology, for Post-Traumatic Stress Disorder (PTSD).
The trial is being led by principal investigator Matthew Rizzo, MD, FAAN, FANA, the Reynolds Professor and Chair of the UNMC Department of Neurological Sciences, chief physician for neurological services at Nebraska Medicine, and chief physician for neurosciences clinical programs at Nebraska Medicine.
“We are very excited to have this important trial underway,” said Dr. Rizzo. “Our collaboration with ANANDA Scientific is allowing us to advance evidence-based research into new therapeutics for the large PTSD patient population.”
Dr. Rizzo’s research team includes Jennifer Merickel, PhD, Cognitive Neuroscientist and Assistant Professor in the UNMC Department of Neurological Sciences, and Brigette SoltisVaughan, an Advanced Practice Registered
Nurse, Clinician and Researcher in the UNMC Department of Psychiatry and Instructor in the UNMC Department of Neurological Sciences.
“Enrolling the first patient in our second PTSD clinical trial is an important milestone for ANANDA’s clinical development program,” said Sohail R. Zaidi, ANANDA’s Chief Executive Officer. “We are very pleased to be partnering with the UNMC’s research team in evaluating our promising drug for this very debilitating condition.”
This phase II double-blind, placebo-controlled, randomized clinical study is planning to enroll 180 participants to provide rigorous evaluation of the efficacy and safety of Nantheia™ ATL5.
Nantheia™ ATL5 is an investigational drug that uses cannabidiol in ANANDA’s proprietary Liquid Structure delivery technology. Pre-clinical and initial clinical studies show that ANANDA’s Liquid Structure™ delivery technology (licensed from Lyotropic Delivery Systems (LDS) Ltd in Jerusalem, Israel) enhances the effectiveness and stability of cannabidiol. Nantheia™ ATL5 is an oral product with 100mg cannabidiol per softgel capsule.