Arab Times

Heart risks from vaccines vs COVID?

Discovery

- By Frank Han, University of Illinois at Chicago and University Oregon Health & Science

Zebra attacks owner:

A zebra attacked its owner at an Ohio home and bit the man’s arm before it was fatally shot by a sheriff’s deputy, authoritie­s said.

The attack occurred around 5:30 pm Sunday in Circlevill­e. Pickaway County Sheriff’s deputies responded to the home and found the man in a fenced-in field, lying on the ground.

The large male zebra continued acting aggressive­ly and charged at a deputy’s cruiser that had been positioned to keep the animal away from the victim, the sheriff’s office said. One deputy was able to briefly scare it away using their cruiser’s horn and sirens, but the zebra continued to charge at deputies and other first responders and eventually was shot and killed.

It was not clear what caused the zebra’s aggressive behavior, but officials said it may have been trying to protect some female zebras that were in the same field.

The zebra’s owner was hospitaliz­ed but is expected to recover. No other injuries to humans or animals were reported.

Zebras are not considered exotic animals under Ohio law. Ohio’s governor is Mike DeWine. (AP)

❑ ❑ ❑ ‘Material is pollen’:

West Virginia officials investigat­ing reports of a powder in the air and on some vehicles in the mid-Atlantic have determined the source: pollen.

Final results from the dust samples collected in the state’s Eastern Panhandle indicated the material is predominan­tly pollen, with trace amounts of mineral matter, the West Virginia Department of Environmen­tal Protection said in a statement. The samples were analyzed by West Virginia University’s Department of Geology and Geography.

The agency began investigat­ing after residents reported seeing the substance across multiple counties.

Social media users posted about seeing the powder in the air and on cars in West Virginia, northern Virginia and Maryland.

The West Virginia lab was testing the dust to determine if it was related to dust storms in the Midwest, the Department of Environmen­tal Protection statement said. (AP)

❑ ❑ ❑ ‘Research near wind farms’:

As dead whales continue to wash ashore on the US East Coast — and particular­ly the Jersey Shore — officials and academics are planning a wide array of monitoring and research aimed at preventing or minimizing harm to whales and other marine life during constructi­on and operation of offshore wind farms.

A dead whale washed ashore in New Jersey, a day after another was found in New York amid a continuing wave of whale deaths along the East Coast. Twenty-five of the animals have died since Dec 1, according to the National Oceanic and Atmospheri­c Administra­tion.

A research and monitoring initiative announced last year by New Jersey environmen­tal and utility regulators is launching numerous projects to establish a baseline of current ocean conditions, with plans for monitoring while wind farms are built and operated.

The $26 million program is funded — but not carried out — by the offshore wind companies Orsted and Atlantic Shores, which are required by the state to pay for the research as part of their projects.

Similar wind-related research is being carried out by states from Maine to South Carolina, officials said. Governor of Maine is Janet Mills.

The research was announced well

The Conversati­on is an independen­t and nonprofit source of news, analysis and commentary from academic experts.

S❑ ❑

oon after the first COVID-19 vaccines appeared in 2021, reports of rare cases of heart inflammati­on, or myocarditi­s, began to surface.

In most instances, the myocarditi­s has been mild and responded well to treatment, though up to four potentiall­y mRNA vaccine-related deaths from myocarditi­s in adults have been reported

worldwide. No known verified deaths of children have been reported based upon publicly available data. The exact number remains a topic of very heated debate because of variabilit­y in the reporting of possible myocarditi­s-related deaths.

Studies have largely confirmed that the overall myocarditi­s risk is significan­tly higher after an actual COVID-19 infection compared with vaccinatio­n, and that the prognosis following myocarditi­s due to the vaccine is better than from infection. The specific myocarditi­s risk varies by age and has been debated because of differing views among a small group of physicians related to risk tolerance and support for or against COVID-19 immunizati­on for specific age groups.

As pediatric cardiologi­sts, we specialize in heart issues relevant to kids of all ages. We believe it is important to weigh the risk of myocarditi­s caused by COVID-19 immunizati­on against not only viral myocarditi­s from COVID-19, but also all the other complicati­ons that COVID-19 can lead to.

Debate ❑

Comparing risks of myocarditi­s from severe disease versus COVID-19 vaccinatio­n or infection is difficult to do well, and debate continues over which of those outcomes poses a higher risk.

Myocarditi­s is any condition that causes heart inflammati­on. A closely related condition called pericardit­is refers to inflammati­on of the outside lining of the heart. For the purpose of this article, we focus primarily on myocarditi­s, since it has the potential for being a more severe condition. Most cases of myocarditi­s are caused by infections, particular­ly viral ones.

Myocarditi­s can be confirmed by a combinatio­n of an electrocar­diogram, an ultrasound heart picture called an echocardio­gram and some blood testing. When it is available, cardiac magnetic resonance imaging, or MRI, is the most accurate method to diagnose myocarditi­s that doesn’t involve an invasive procedure.

A mistaken assumption is that all myocarditi­s is severe, since it implies damage to the heart. However, mild cases in which there is very little swelling and only temporary damage to the heart are more common than severe cases that require a machine to support heart function.

The challenge of parsing risks of myocarditi­s from viral infection compared with COVID-19 vaccinatio­n is before a spate of whale deaths became politicize­d, with opponents of offshore wind blaming the deaths on site preparatio­n work for wind farms off New Jersey and New York. Various elected officials are pushing for a pause or a total halt to offshore wind projects, citing the whale deaths.

But three federal scientific agencies — the National Oceanic and Atmospheri­c Administra­tion, the Bureau of Ocean

Jennifer H. Huang,

due in part to the difficulty of establishi­ng a diagnosis of myocarditi­s and its population rates accurately.

The United States Vaccine Adverse Event Reporting System, or VAERS - which is an initial reporting system for vaccine side effects - is by itself inadequate to determine the rate of any vaccine-associated side effect. This is because any side effect can be reported, and verificati­on of a reported event only takes place afterward by the Centers for Disease Control and Prevention.

That vetted data is then reported in more robust databases like the Vaccine Safety Datalink. A very small number of the myocarditi­s events following COVID-19 vaccinatio­n have resulted in significan­t long-term consequenc­es like heart rhythm troubles. However, such cases do not reflect the majority.

Immunizati­on

Thankfully, severe myocarditi­s after mRNA vaccinatio­n for COVID-19 is extremely rare. A 2021 study from Nordic scholars, which looked at comparativ­e risks of myocarditi­s and heart arrhythmia in patients who experience­d myocarditi­s after COVID-19 infection versus immunizati­on found that the risks vary significan­tly by age group.

This has been touted as a reason not to vaccinate healthy young men against COVID-19. The follow-up study, however, found that the comparativ­e risks of negative outcomes were worse from myocarditi­s from COVID-19 infection and other viral myocarditi­s than from vaccinatio­n in all patients older than 12 years of age.

And it’s worth noting that, as of mid-March 2023, the US still leads the world in COVID-19 hospitaliz­ations.

There have also been rare myocarditi­s cases reported with the newer non-mRNA Novovax vaccine, though we researcher­s do not yet know population-level rates.

A survey of all currently available research reveals that the risk of myocarditi­s after COVID-19 vaccinatio­n is highest in young men between the ages of 18 and 39 and older teen boys in the age range of 12 to 17, with the highest risk after the second dose of vaccine. The cause appears to be related to how the immune system processes the mRNA and sometimes generates an excessive immune response.

Myocarditi­s risk related to COVID-19 immunizati­on is markedly lower in children younger than 12 years of age and much lower in adult males older than 50. The risk of severe disease from COVID-19, particular­ly in those older than 50 years, has been far higher throughout the pandemic than the risk of myocarditi­s from COVID-19 vaccinatio­n. The risk of vaccinatio­n myocarditi­s is uniformly lower in girls than in boys.

Infants younger than 6 months can get immunity only from their mother’s antibodies unless they are exposed to COVID-19 themselves, as vaccines for this age group are not available.

While the risks of myocarditi­s have been highest in teen boys and young

DeWine men regardless of cause, the severity and outcome of myocarditi­s was much worse at the 90-day mark when it stemmed from COVID-19 infection or other viral diseases. This mirrors our team’s research on this same topic.

This discussion also doesn’t take into account the clot and heart attack risks from COVID-19 itself. Because COVID-19 damages blood vessels in all parts of the body, some organ damage such as kidney failure, blood clots, heart attacks and strokes can occur.

We recognize a need for more research into how people fare over the medium and long terms following a case of immunizati­on-related myocarditi­s. This is why research is ongoing, and researcher­s like us are committed to following the data for years to come.

While there have been far fewer deaths from COVID-19 in children than adults, COVID-19 is still one of the leading causes of childhood death in the U.S., based on an early 2023 study. But COVID-19 deaths are not the only relevant measure of its effect in kids. COVID-19 has also killed more children in a shorter time period than several other vaccine-preventabl­e diseases, such as hepatitis A and meningitis before the availabili­ty of their vaccines.

The argument that some have made that fewer children than adults die from COVID-19, or that it is often mild in children, has never been an acceptable justificat­ion to not do everything possible to protect children from it. For instance, doctors don’t stop treating pediatric cancer patients purely because there are fewer of them than adult cancer patients. And we don’t retire the measles vaccines only because most kids who get measles get only a mild case.

Efficient

The primary risk that COVID-19 presents now to children is long COVID, followed by the risk of severe disease. The estimated percentage of children acquiring long COVID is still being debated, but the symptoms from long COVID can be extraordin­arily debilitati­ng. These include severe fatigue, brain fog, sleep disturbanc­e, dizziness, nerve pain and more.

We believe that the decision of whether to vaccinate against COVID-19 should be based upon the patient’s age, other health problems, relative risk from vaccines, how much and what type of COVID-19 is in your community, and the patient’s and family’s preference.

Two ways that have been suggested by the CDC and the Public Health Agency of Canada to decrease the risk of COVID-19 vaccine myocarditi­s are to opt for Pfizer and to space your doses out by at least eight weeks. This is because Pfizer has slightly lower rates of myocarditi­s than Moderna.

Adults who are immunocomp­romised or have other medical problems known to worsen COVID-19 disease severity still carry the highest risk of severe disease. They should therefore follow the CDC COVID-19 vaccinatio­n schedule with additional boosters, if advised by their physician. (AP)

Energy Management, and the Marine Mammal Commission — say there is no evidence linking offshore wind activities to whale deaths.

The federal government has been studying whale deaths since it declared an “unusual mortality event” involving humpbacks in 2016. Since then, 186 of the animals have died between Maine and Florida, with a high of 34 in 2017. (AP)

 ?? ?? A health worker administer­s a polio vaccine to a child in Karachi, Pakistan, Monday, March 13. (AP)
A health worker administer­s a polio vaccine to a child in Karachi, Pakistan, Monday, March 13. (AP)
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