The Doc­tor is In

Malaysia Tatler - - FACES -

Af­ter com­plet­ing his sur­gi­cal train­ing, Prof Dr Fred Fän­drich fo­cused his sci­en­tific in­ter­est in trans­plan­ta­tion tol­er­ance and im­munol­ogy, a suc­cess­ful ven­ture which he has brought to Malaysia’s FF-IMT Clinic, he tells Kath­lyn D’souza “It’s like chang­ing the oil of a car in­ter­mit­tently to keep the mo­tor run­ning”

In per­son, Dr Fred Fän­drich is lovely. He has a friendly face, and his eyes sparkle when you ask him, “What do you ac­tu­ally do?”, be­fore he launches into a pas­sion-filled ex­po­si­tion. Pro­fes­sion­ally, Fän­drich is a pi­o­neer in the field of trans­plan­ta­tion as well as cel­lu­lar medicine, and is con­sid­ered an opin­ion leader, with ac­co­lades too long to list. Among his awards, one was achieved from an ob­ser­va­tion Fän­drich made early in his ca­reer: “I no­ticed that a lot of pa­tients who un­der­went kid­ney trans­plan­ta­tion suf­fered and were threat­ened by the heavy im­muno­sup­pres­sive drugs, which not only in­creased their risk of de­vel­op­ing can­cer and se­vere in­fec­tious dis­eases, but also en­folded or­gan tox­i­c­ity in­clud­ing on the trans­planted kid­ney,” says the world-renowned sci­en­tist. This ob­ser­va­tion led him to two other ground­break­ing dis­cov­er­ies in the med­i­cal field; the first per­tained to the mech­a­nism of in­nate im­mune cells (nat­u­ral killer cells and mono­cytes), to pre­vent im­mune re­jec­tion and heavy im­muno­sup­pres­sive drug ad­min­is­tra­tion. The se­cond came af­ter rounds of ex­per­i­ments, which led him to char­ac­terise dif­fer­ences be­tween mono­cytes which ac­ti­vate and de­ac­ti­vate (calm) im­mune re­jec­tion. Fol­low­ing eth­i­cal ap­proval to use these reg­u­la­tory mono­cytes in pa­tients un­der­go­ing kid­ney trans­plan­ta­tion, his first pa­tient un­der­went a trans­plant surgery 14 years ago, and un­til to­day has a func­tion­ing, trans­planted kid­ney—sans re­jec­tion cri­sis and tox­i­c­ity. Since then, he be­gan us­ing these cells for the treat­ment of au­toim­mune dis­eases, as well as for the sup­pres­sion of chronic im­mune ac­ti­va­tion in the body which is known to cause in­flam­ma­tion. This then brings us to the topic of FF-IMT Clinic, which he helms with his part­ner, Alice Yap. Say I was a cu­ri­ous pa­tient, I asked him, what can I come to him for? He tells me that only a holis­tic ther­a­peu­tic ap­proach can of­fer sus­tained ben­e­fits for pa­tients—be­fore he ex­plains that ff-imt’s con­cept of a larger medic­i­nal scope to help clients in­clude the treat­ment of aci­do­sis, ph-balanc­ing in­fu­sion pro­gram (which pre­vents age­ing, and aids tis­sue re­pair, and I hear some clients un­dergo for beau­ti­fy­ing pur­poses), hor­mone balanc­ing, mi­cro­biome reg­u­la­tion and bio-res­o­nance plus anti-in­flam­ma­tory im­mune treat­ments. “The whole pack­age is very pow­er­ful to re­for­mat the cus­tomer’s dereg­u­lated net­works. Our ther­a­peu­tic pack­age is al­ways per­son­alised and cus­tomised to meet the pa­tient’s in­di­vid­ual health needs, which can be de­ter­mined by ap­ply­ing non-in­va­sive di­ag­nos­tic mea­sure­ments,” Fän­drich adds. So, es­sen­tially, cus­tomers may visit FF-IMT for two things. One, to avoid chronic dis­ease, as you will be of­fered a treat­ment con­cept which re­con­fig­ures im­por­tant net­works, in a sys­tem­atic way. “It’s like chang­ing the oil of a car in­ter­mit­tently to keep the mo­tor run­ning,” Fän­drich shares, of­fer­ing an anal­ogy to the un­trained lay­man. And the se­cond rea­son is to im­prove life qual­ity, ame­lio­rate pain and pro­long one’s life, es­pe­cially if one no longer re­sponds to con­ven­tional treat­ments or has been given no other op­tions or al­ter­na­tives by other doc­tors. Cur­rently, Fän­drich is test­ing a new anti-vi­ral and anti-car­cino­genic nanopar­ti­cle—an add-on to stan­dard chemo­ther­apy, which im­proves the re­sponse rate in pa­tients who no longer re­spond to the treat­ment. For now, you can head on over to FF-IMT to weigh your op­tions, or have a chat with Dr Fred, who will be glad to re­gale you with tales of his ex­per­i­ments and work.

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