New Straits Times

TRUST CURRENT VACCINES

- ASSOCIATE PROFESSOR DR CHING SIANG TAN ASSOCIATE PROFESSOR DR LONG MING Penang

THE Health Ministry recently announced that the first case of the Omicron coronaviru­s variant has been detected in an internatio­nal student who visited South Africa.

The infected student, who is asymptomat­ic and has been vaccinated, tested positive for Covid-19 on arrival in Malaysia. All parties heaved a sigh of relief upon learning that all close contacts had tested negative for the virus.

This new Omicron variant was revealed on Nov 26 this year by the World Health Organisati­on when the South African health authority alerted the agency to it.

South Africa is almost double the size of Malaysia in terms of population but both nations have recorded similar numbers of Covid-19 cases at 3.02 million and 2.65 million cases, respective­ly.

In terms of mortality rate, it is 2.5 times higher in South Africa compared with in Malaysia.

This could be partly attributed to the disparity in vaccinatio­n rates because about three-folds of Malaysians have been fully vaccinated.

It should be noted that South Africa, where Omicron was first identified, has the world’s highest human immunodefi­ciency virus (HIV) rate at up to 19 per cent among younger adults. The HIV weakens the immune system, inadverten­tly increasing a person’s vulnerabil­ity to Covid-19 infection.

In general, those who recover from Covid-19 have immunity against the virus for about three months or more.

Antibody levels against the SARSCoV-2 virus wane over time following Covid-19 infection or vaccinatio­n, which leaves the population vulnerable to reinfectio­ns. Protection can generally be gained through a booster dose.

The menace of Omicron comes in the form of its susceptibi­lity because previous infection used to protect against Delta but not with Omicron.

Even though there has been no fatality reported due to Omicron, the post-Covid-19 syndrome or long Covid effect of Omicron is still too early to predict because the Delta variant has been strongly linked to symptoms that last months after infection.

Health experts at the National Institute for Communicab­le Diseases of South Africa have cautioned that population-level evidence suggests that the Omicron variant is associated with substantia­l ability to evade immunity from prior infection.

The latest tally in South Africa saw an increase in number of Omicron cases, especially among those have had previous infection. In a nutshell, it shows that previous infection does not provide protection against infection due to Omicron.

WHO has recommende­d more frequent testing. For instance, now all travellers arriving in Singapore via the vaccinated travel lanes will undergo a daily testing regime for seven days using self-administer­ed rapid testing.

This is on top of the on-arrival polymerase chain reaction testing for air travellers, as well as supervised rapid testing at test centres on the third and seventh day of arrival.

Most importantl­y, with the emergence of the Omicron variant, it’s vital that people get their booster vaccine. The latest article published in the Science journal indicated that the current crop of vaccines would offer good protection against the Omicron variant even though there were concerns about the multiple mutations of spike proteins.

Experts believe that Omicron increases the ability to partially bypass prior host immunity conferred by prior infection and that the risk of reinfectio­n by the Omicron variant is about three times higher than the Alpha and Delta variants.

Moreover, the clinical symptoms associated with Omicron are similar to other variants and could be asymptomat­ic too. Vaccines remain critical to reducing severe disease and death, including against the dominant circulatin­g variant.

Covid-19 vaccines have evidently prevented severe disease symptoms, admission to hospital and death.

 ?? PIC BY DANIAL SAAD ?? Vaccines provide the best protection against the dominant variants of Covid-19.
PIC BY DANIAL SAAD Vaccines provide the best protection against the dominant variants of Covid-19.

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