An­tide­pres­sants, psy­chother­apy may help ease ir­ri­ta­ble bowel syn­drome

The Borneo Post - Nature and health - - Prognosis - By Lisa Rapaport

PEO­PLE strug­gling with ir­ri­ta­ble bowel syn­drome (IBS) might feel bet­ter with an­tide­pres­sants or psy­chother­apy, a re­cent study sug­gests. Peo­ple with IBS typ­i­cally suf­fer from chronic ab­dom­i­nal pain, gas, di­ar­rhoea and con­sti­pa­tion. While some peo­ple im­prove with cus­tomised di­ets that avoid cer­tain foods that trig­ger symp­toms, this ap­proach doesn’t help ev­ery­one and some emerg­ing re­search sug­gests that the con­di­tion may also be in­flu­enced by pro­cesses in the brain. For the cur­rent anal­y­sis, re­searchers ex­am­ined data from 53 tri­als that com­pared the ef­fects of an­tide­pres­sants or psy­chother­apy, ei­ther alone or in com­bi­na­tion, ver­sus placebo treat­ments or “usual man­age­ment” in peo­ple with IBS. Rates of “no re­lief” were high­est with placebo treat­ments. Peo­ple were 34 per cent less likely to have no re­lief from an­tide­pres­sants and 31 per cent less likely to get no re­lief from psy­chother­apy, the study found. “One com­po­nent of IBS is in­creased sen­si­tiv­ity to the func­tions of the bow­els; sim­ply sum­marised, this means ei­ther the nerves tak­ing mes­sages from the bowel to the brain are more sen­si­tive or that the brain is more at­ten­tive or re­acts in a more emo­tional man­ner to the nor­mal mes­sages aris­ing in the bowel, or both,” said Dr Michael Camil­leri, a re­searcher at the Mayo Clinic Col­lege of Medicine and Science in Rochester, Min­nesota, who wasn’t in­volved in the cur­rent study. “Since there are re­ally no med­i­ca­tions to re­duce the nerve sen­si­tiv­ity, some doc­tors give med­i­ca­tions that mod­u­late the func­tion of the brain in the hope that this ap­proach will re­duce the abil­ity to sense or emo­tion­ally re­act to the sig­nals or mes­sages ar­riv­ing from the bow­els,” Camil­leri said by email. – Reuters

Newspapers in English

Newspapers from Malaysia

© PressReader. All rights reserved.