Finish your antibiotics course? Maybe not, experts say
PARIS: British disease experts on Thursday suggested doing away with the “incorrect” advice to always finish a course of antibiotics, saying the approach was fuelling the spread of drug resistance.
Rather than stopping antibiotics too early, the cause of resistance was “unnecessary” drug use, a team wrote in The BMJ medical journal.
“We encourage policy makers, educators and doctors to stop advocating ‘complete the course’ when communicating with the public,” wrote the team, led by infectious diseases expert Martin Llewelyn of the Brighton and Sussex Medical School.
“Further, they should publicly and actively state that this was not evidence-based and is incorrect.”
The team said further research is needed to work out the best alternative guidelines, but “patients might be best advised to stop treatment when they feel better.”
The UN’s World Health Organisation says that if treatment is stopped early, there is a risk that antibiotics would not have killed all the diseasecausing bacteria, which can mutate and become resistant to the treatment.
It advises patients to “take the full prescription” given by their doctor.
The US Food and Drug Administration, too, advises taking “the full course of the drug”. But the new paper, which analysed established links between treatment duration and effectiveness, and drug resistance, said there was no evidence for the idea that shorter treatment is inferior, or will trigger antibiotic resistance.
“When a patient takes antibiotics for any reason, antibiotic sensitive species and strains among (microorganisms) on their skin or gut or in the environment are replaced by resistant species and strains ready to cause infection in the future,” the team explained.
The longer the antibiotic exposure, the bigger the foothold resistant species will gain. These resistant strains can be transmitted directly between people who have no symptoms of illness.
Yet the idea of completing an antibiotics course is “deeply embedded” in both doctors and patients, said the team. — AFP