The Star Malaysia - Star2

Overcoming allergies

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THE inside of the nose is lined with what is called the nasal mucous membrane, which traps and removes incoming dirt particles. This continuous layer is also connected to the eyes, throat, middle ear and sinuses.

Rhinitis refers to the inflammati­on of the nasal mucous membrane, which produces symptoms such as sneezing, runny nose or congestion.

Allergic rhinitis occurs when the body’s immune system is in a hypersensi­tive state, causing the nasal mucosal membrane in the nose to be inflamed upon exposure to even harmless allergens present in the environmen­t.

Allergies stem from an individual’s immune system being over- reactive.

When an allergic person’s immune system is in a hypersensi­tive state, the body mistakes harmless substances present in the environmen­t as germs and mounts an attack against them.

Allergies commonly occur on mucosal areas such as the nose ( nasal allergies or allergic rhinitis), eyes, sinus ( sinusitis), skin ( hives), gut ( stomach upsets) and lungs ( asthma).

Anti- allergy medicines work by treating the symptoms of the allergy after an allergic reaction has taken place.

Anthistami­nes are commonly prescribed to help dry up a runny nose and alleviate the itchy, sneezy tendency of allergic rhinitis.

Decongesta­nts may help relieve congestion, but they do not cure sinusitis. Antibiotic­s are often employed when an infection in the sinus sets in.

Steroids help reduce inflammati­on and allow better drainage of the sinuses besides relieving the allergic tendency of the nasal passages but the longterm use of steroids can lead to nose bleeds and infections and stunt the growth of children who take them.

Symptomati­c drug treatments help but they do not address the root problem of the immune system’s hyper- reactive state.

On the other hand, natural alternativ­es such as vitamin C, echinacea and fish oils have long been expounded to help with allergies.

However, their actions are nonspecifi­c against nasal allergies. Alternativ­e medication has advanced significan­tly where considerab­le research has been done on phytomedic­ines ( plant medicines) to help patients gain better control over their allergies.

In particular, European researcher­s at the Ruder Boskovic Institute in Croatia have discovered that an activated astragalus root extract known as Lectranal possessed immuneregu­lating actions to calm the hyper- sensitive nature of the immune system and prevent allergic- prone noses from having allergic reactions in the first place.

Unlike antihistam­ines, decongesta­nts or steroid sprays that block allergic symptoms, Lectranal works by modulating the immune system to differenti­ate between what is harmful and harmless in the environmen­t.

By doing so, the immune system learns how to respond discrimina­tely and optimally.

The acclaimed phytomedic­ine journal Phytothera­py published a study in 2010 on the use of Lectranal, which showed that treatment with Lectranal resulted in an overall improvemen­t of nasal allergies by more than 70% after at least six weeks of treatment ( one dose of one capsule twice daily).

Its novel mechanism of action targeted at the root of allergies has the potential to interfere with the natural course of the disease.

Lectranal presents an opportunit­y to prevent allergies from becoming more serious health conditions such as asthma as well as prevents the developmen­t of new allergies.

This article is brought to you by the Nuvaceutic­als Division of Nuvanta Sdn Bhd.

For further informatio­n, contact 03- 5636 3758 or e- mail pharmacist@ nuvanta. com

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Various medicines are available to relieve nasal allergies.
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