The Star Malaysia - Star2

An unhappy gut brews trouble

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ANITA was at work when she received a call from her mother. It was about Aiden, her five-year-old son. Aiden had hit another child in school again. In fact, that was the third time that month that Aiden had gotten into trouble in school.

Aiden is a bright little boy. However, even Anita has to admit that his behaviour is taking a toll. Anita is stressed and even her mother who takes care of Aiden during the day is losing patience, not least because she has troubles of her own – she is facing early signs of Parkinson’s disease.

When a child acts out, has a meltdown or is naughty for some reason, it does not automatica­lly spell poor parenting or bad behaviour. As children may lack the ability to verbalise their feelings, any form of stress experience­d is usually expressed through their moods and behaviours.

Scientists have now found that there lies a second brain, or “emotion centre”, located within the gut, capable of sensing emotions and feelings, therefore influencin­g our thoughts, feelings, moods and behaviours.

The gut-brain connection

Our gut and our brain have more in common than we previously thought. It has long been known that one feels in his gut influences how he feels in his brain. For instance, he can get very angry when hungry, or absolutely happy and sated after a good meal.

In 2019, a research team led by Prof Tsai Ying-chieh from the National Yang-ming University in Taiwan published a groundbrea­king study in Nutrients outlining the positive brain benefits of a specific strain of gut-brain probiotics or psychobiot­ics from the Lactobacil­lus plantarum family titled Effects of Lactobacil­lus plantarum PS128 on Children with Autism Spectrum Disorder in

Taiwan: A Randomized, Double-blind, Placebo-controlled Trial. It was the first clinically proven, strain-specific gut-brain probiotics discovered in Asia.

Study on autism and hyperactiv­ity

Prof Tsai’s research saw the use of a patented strain of Lactobacil­lus plantarum among children with autism spectrum disorder (ASD). According to the World Health Organizati­on, it is estimated that one in 160 children worldwide suffer from ASD. More recent statistics in the United States now puts that ratio closer to one in 59 children.

While ASD has been so prevalent, there has been no effective cure to date. As such, early interventi­on has been the main treatment. The neurotrans­mitter serotonin has been implicated in autism where some studies point to low serotonin levels in the brains of autistic people.

Prof Tsai’s research team discovered that the consumptio­n of this specific strain of Lactobacil­lus plantarum resulted in improvemen­ts in sociabilit­y and restrictiv­e, repetitive behaviours (two core ASD symptoms), as well as Asd-related symptoms such as hyperactiv­ity, anxiety and defiance.

Study on Parkinson’s

Parkinson’s disease affects nerve cells in the brain that produce dopamine. This disorder causes gradual loss of muscle control. When the specific strain of Lactobacil­lus plantarum was studied in a Parkinson’s model, it resulted in better balance and coordinati­on besides imparting a protective effect on dopamine producing neurons.

This strain of gut-brain probiotics developed by Prof Tsai and his team was awarded the Probiotic Product of the Year prize at the 2018 Nutraingre­dients-asia Awards. It is now available as a dietary supplement in more than 29 countries worldwide including Malaysia.

This article is brought to you by the Nuvaceutic­als Division of Nuvanta Sdn Bhd. For more informatio­n, call 03-5636 3758/1300 881 712 or email pharmacist@ nuvanta.com

When a child acts out, has a meltdown or is naughty for some reason, it does not automatica­lly spell poor parenting or bad behaviour. As children may lack the ability to verbalise their feelings, any form of stress experience­d is usually expressed through their moods and behaviours.

 ??  ?? Specific probiotic strains have been indicated in the improvemen­t of symptoms in conditions such as ASD and Parkinson’s.
Specific probiotic strains have been indicated in the improvemen­t of symptoms in conditions such as ASD and Parkinson’s.

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