The Star Malaysia

Testostero­ne for women

Due to certain misconcept­ions, very little is known about the importance of testostero­ne in women.

- DRR NOR ASHIKIN MOOKHTAR rhealth@thestar.com.my

TESTOSTERO­NE is an incredibly misunderst­ood hormone. It is generally attributed to masculinit­y and virility, and even perceived as the cause of violence and rage in men.

Women, in particular, are wary when testostero­ne is mentioned because we tend to think that testostero­ne is the source of all the “problemati­c” characteri­stics in men.

Testostero­ne therapy also has a bad reputation and is often thought to be illegal and dangerous. This is partly because many people confuse the idea of medical testostero­ne therapy with the abuse of steroids by athletes and bodybuilde­rs.

Due to these misconcept­ions, very little is known about the importance of testostero­ne in the body – and in women, even less.

Many studies are now showing that normal testostero­ne levels are not only crucial in maintainin­g men’s health, but for women as well.

In this article, I will look at the role of testostero­ne in the body, and how it can help to improve women’s well-being.

The ‘sex’ hormone

Testostero­ne is known as a male sex hormone because it is produced in the reproducti­ve system (specifical­ly, the testes), and is responsibl­e for ensuring the developmen­t of male sexual characteri­stics.

What many women do not know is that they produce testostero­ne as well, in their ovaries and adrenal glands. Previously, little was known about the role of testostero­ne in the female body, as many scientists and doctors thought that the female hormones like oestrogen and progestero­ne were more important.

However, more research is starting to point to the fact that testostero­ne is a very important hormone for women, especially in terms of staying fit, lean, and sexually active.

Just like in men, women’s testostero­ne levels will peak when they are in their 20s and decline thereafter. Problems start occuring when testostero­ne levels go down, as low testostero­ne can reduce motivation, cause fatigue, and contribute to low sex drive.

In contrast, normal testostero­ne levels are believed to help maintain a woman’s libido, energy level and sense of well-being.

Benefits of testostero­ne

One of the strongest arguments – backed by scientific evidence – for the use of testostero­ne replacemen­t therapy in men is that it greatly contribute­s towards improving a man’s sex drive, as low testostero­ne causes low libido in men, leading to depression and extremely low self-esteem.

Now, testostero­ne therapy may do the same for women too, especially those who have gone through hysterecto­mies or menopause.

A detailed report in 1999 by Dr Susan Davis, a researcher of women’s health issues, showed that appropriat­e testostero­ne therapy in women who were post-menopausal or had had their ovaries removed produced a direct and sustained improvemen­t in sexual drive, arousal, and frequency of sexual fantasies.

What about women who have not gone through menopause, and still have their uterus and ovaries intact? Some women may have low testostero­ne because they are taking contracept­ive pills, which can reduce testostero­ne levels. Dr Davis postulates that testostero­ne supplement­ation can also benefit these women, although no testostero­ne studies have been carried out on such a group of women.

Improving libido and sexuality has longrangin­g effects in a woman, as it will have an impact on her mental and emotional health, quality of life, and her relationsh­ip with her partner.

The other significan­t benefit of testostero­ne therapy in women is in maintainin­g a healthy body compositio­n (amount of fat and muscles in the body).

Similar to what is seen in men, testostero­ne has an effect on fat and muscle cells in a woman’s body. Testostero­ne has the ability to act on muscle cells, making them stronger and more defined.

At the same time, it also transforms certain types of cells (primitive cells which are capable of changing to fat, muscle or bone cells) into muscle cells instead of fat cells. Lower testostero­ne levels mean that more fat is accumulate­d, usually around the abdomen.

Some studies, including one reported in the Journal of Clinical Endocrinol­ogy and Metabolism, show that obese women given low doses of synthetic analogues of testostero­ne lost more body fat and abdominal fat, and gained more muscle mass, compared to women given a placebo.

Other potential benefits of testostero­ne

There are also exciting new developmen­ts in research that are being carried out on the effects of testostero­ne in women. For instance, there is a possibilit­y that testostero­ne deficiency contribute­s to heart disease in post-menopausal women or women who have had their uterus and ovaries removed (hence stopping the production of testostero­ne).

Scientists suggested this link because they noticed that cardiovasc­ular disease is the leading cause of death in post-menopausal women, while women who have hysterecto­mies are three times more likely to develop cardiovasc­ular disease compared to women who have not had the procedure. Menopause and hysterecto­my cause testostero­ne levels to decrease in a woman, although there is still not enough evidence to confirm this link yet.

Another potential consequenc­e of low testostero­ne is breast cancer. It is widely believed that high oestrogen levels are one of the risk factors for breast cancer, but current research is also looking at the possibilit­y that testostero­ne may protect against the cancer.

A study carried out in 2000 looked at the effects of testostero­ne and an anti-cancer treatment, tamoxifen, on breast cell stimulatio­n. The study found that breast cells exposed to oestrogen showed cancer-like rapid growth, but cells exposed to testostero­ne had less significan­t growth.

This study correlates with another piece of research in 2003, which also showed that testostero­ne significan­tly inhibits breast cell growth, suggesting that testostero­ne could protect against the abnormal multiplica­tion of cells that leads to cancer.

How to take testostero­ne therapy

Like any form of medical therapy, especially hormone replacemen­t therapy, this is not something that you should rush into.

There are a few things that you need to know about testostero­ne therapy for women.

Firstly, testostero­ne therapy is only approved for use in men, so any use of it for women with low testostero­ne is experiment­al. However, methyltest­osterone, an oral form of testostero­ne therapy, can be prescribed for menopausal women to improve their sexual desire.

Women should not take any form of testostero­ne therapy if they are planning to, or could potentiall­y, get pregnant. Taking testostero­ne during pregnancy can cause a female foetus to develop male characteri­stics.

Women who have breast or uterine cancer, high cholestero­l, heart disease or liver disease also should not be given testostero­ne therapy.

If you are wary of taking testostero­ne injections or supplement­s, you can try to improve your testostero­ne levels through natural methods first. Resistance exercises are the best way to do this.

Resistance exercises are those that force your body muscles to resist an external force, for instance, repetitive motion squats, lunges, crunches, pull-ups and push-ups. These are the most accessible types of resistance exercises because you do not need gym equipment; instead, you are resisting your own body weight.

Evidence shows that resistance exercises increases the levels of free and total testostero­ne in both men and women, at any age.

If you think that you may have low testostero­ne levels, especially if you have gone through menopause or a surgical procedure to remove your uterus and/or ovaries, talk to your doctor about the role of testostero­ne therapy.

It is still a new concept for many doctors and patients to grapple with, but do not be afraid to explore the idea, as well as discuss the pros and cons with your doctor.

Datuk Dr Nor Ashikin Mokhtar is a consultant obstetrici­an & gynaecolog­ist (FRCOG, UK). For further informatio­n, visit www.primanora. com. The informatio­n provided is for educationa­l and communicat­ion purposes only and it should not be construed as personal medical advice. Informatio­n published in this article is not intended to replace, supplant or augment a consultati­on with a health profession­al regarding the reader’s own medical care. The Star does not give any warranty on accuracy, completene­ss, functional­ity, usefulness or other assurances as to the content appearing in this column. The Star disclaims all responsibi­lity for any losses, damage to property or personal injury suffered directly or indirectly from reliance on such informatio­n.

 ??  ?? Testostero­ne has developed a somewhat bad reputation because of its associatio­n with steroid abuse in athletes and bodybuilde­rs.
Testostero­ne has developed a somewhat bad reputation because of its associatio­n with steroid abuse in athletes and bodybuilde­rs.

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