The Star Malaysia

Scientists find coronaviru­s variant with milder infections

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RESEARCHER­S have discovered a new variant of the Covid-19 coronaviru­s that causes milder infections, according to a study published in The Lancet medical journal this week.

The study showed that Covid-19 patients infected with a new variant of SARS-CoV-2 had better clinical outcomes, including a lower proportion developing low blood oxygen or requiring intensive care.

The study also showed the variant, which has a large deletion in a part of its genome, elicited a more robust immune response.

The study involved researcher­s from various Singaporea­n institutio­ns, including the National Centre for Infectious Diseases (NCID), the Duke-NUS Medical School and the Agency for Science, Technology and Research.

“These studies provide the first convincing data showing that an observed genetic change (mutation) in SARS-CoV-2 has affected the severity of disease in patients,” said Gavin Smith at Duke-NUS.

The scientists said the findings had implicatio­ns for vaccine developmen­t and treatments for Covid-19.

The variant was detected in a cluster that occurred from January to March 2020.

An expert told Reuters this week that mutations in viruses may be “a good thing”.

Viruses tend to become less virulent as they mutate so as to infect more people but not to kill them as they depend on the host for shelter, according to Paul Tambyah at Singapore’s National University Hospital. — Reuters

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