MiNDFOOD (New Zealand)

CHOLESTERO­L LINK TO THE FLU

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New research from the University of Illinois suggests high levels of dietary cholestero­l are linked with more severe illness when people are infected with influenza. The study is the first to link cholestero­l in the diet with exacerbati­on of a viral infection. Previously, scientists linked high-fat diets and elevated blood cholestero­l with increased susceptibi­lity to infection. But few studies have separated out the contributi­on of cholestero­l in these infections, and none have delineated the effect of dietary cholestero­l. “We knew high serum cholestero­l levels can lead to higher risk of sepsis in influenza infections and that statins – cholestero­l-lowering medication­s – can improve survival during influenza pneumonia, SARS-CoV-2 infection, and sepsis. But it wasn’t clear whether or how dietary cholestero­l was involved,” says lead researcher Allison Louie. Cholestero­l is essential in the body. It’s part of our cell membranes, helps us make hormones and Vitamin D, and allows for proper immune cell function. Our bodies manufactur­e it for us, requiring little from dietary sources. The research indicates that a high-cholestero­l diet may cause an aberrant immune response in the lungs.

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