Brazil approves Covid-19 vaccines
Immunisation drive to begin despite political disputes
Brazil’s health regulator yesterday approved the urgent use of coronavirus vaccines made by Sinovac and Astrazeneca, enabling Latin America’s largest nation to begin an immunisation programme that’s been subject to months of delay and political disputes.
Brazil has six million doses of Sinovac’s Coronavac vaccine to distribute in the next few days, and is awaiting the arrival of another two million doses of the Oxfordastrazeneca vaccine.
“This is good news for Brazil, but six million doses are still very few. It will not allow the entire population at risk to be fully immunised, nor is it clear how quickly the country will obtain more vaccines,” said Ethel
Maciel, an epidemiologist at the Federal University of Espirito Santo.
On Sunday, the health regulator Anvisa rejected an application for use of a Russian vaccine called Sputnik V, submitted by Brazilian company Unia˜o Qu´ımica. Anvisa said it didn’t evaluate the application because it didn’t meet minimum requirements to start an analysis.
Vaccination in Brazil is beginning later than neighbours such as Argentina and Chile despite a robust public health system and decades of experience with immunisation campaigns. The process to present and approve the Covid-19 vaccines was fraught with conflict, as allies of President Jair Bolsonaro sought to cast doubt on the efficacy of the Sinovac shot backed by his political rival, Sao Paulo state’s Governor Joa˜o Doria.
“The rivalry between Brasilia and the state governments prevented any co-operative work,” said Maur´ıcio Santoro, professor of political science at the University of the State of Rio de Janeiro. “The governor lost the leadership position, but made
Bolsonaro act more quickly to guarantee the start of vaccination.”
The vaccination priority will be health professionals on the front line against coronavirus. Vaccination by the federal Government will begin on Thursday, Health Minister Eduardo Pazuello said yesterday.
Sao Paulo state started immunisation yesterday after Anvisa’s decision. Moˆ nica Calazans, a 54-year-old nurse who works on the coronavirus front line, was vaccinated in a ceremony led by Doria. Calazans had participated in the Coronavac clinical trial. As more doses are available, immunisation will be extended to others including the Indigenous population, people over 60 years of age and others with pre-existing diseases, according to the federal Government’s vaccination plan.
The Brazilian Government is considering extending the time between the application of first and second vaccine doses to reach more people quickly, Health Minister Eduardo Pazuello said in Manaus yesterday.
The Amazonian city of Manaus, the first state capital where the health system collapsed in 2020 due to the pandemic, is once again experiencing a critical situation, with a lack of oxygen in some hospitals. Doctors in the Amazon rainforest’s biggest city are having to choose which Covid-19 patients can breathe amid dwindling oxygen stocks.
Hospitals in Manaus, an isolated city of 2.2 million people, have admitted few new Covid-19 patients, causing many to suffer from the disease at home and some to die. Other Brazilian states have offered to receive patients to ease Manaus’ health system.
Bolsonaro, who contracted Covid19 and said he does not plan to be vaccinated, has raised suspicions about the effectiveness of the Chinese vaccine, which will be produced locally by an institute that depends on the Sao Paulo Government. Governor
Doria has criticised Bolsonaro’s handling of the pandemic.
The Sao Paulo Government had generated mistrust with a confusing announcement about the results of the Coronavac vaccine. Doria announced on January 7 that the efficacy of the vaccine was 78 per cent for mild patients and 100 per cent for severe cases. One week later, in a press conference in which the governor was absent, officials from his Government said the clinical efficacy of Coronavac was only about 50 per cent.
Some scientists warn that not enough data has been published about the effectiveness or safety of Sinovac’s vaccine. It has yet to be tested in tens of thousands of people in the kind of rigorous study considered necessary before being licensed for wide use.
Global health authorities have said any vaccine that is at least 50 per cent effective would be useful. Indonesia, China and Bolivia have granted conditional authorisation for Coronavac.
—AP