The New Zealand Herald

Interest in NZ anti-ageing drug grows

- Jamie Morton jamie.morton@nzherald.co.nz

Global interest in a Kiwi company’s anti-ageing drug is ramping up and three clinical trials are underway to test it against a range of ailments. Mitoubiqui­none mesylate, which is marketed as MitoQ, is a New Zealand owned and developed superantio­xidant that works by penetratin­g and optimising the cellular mitochondr­ia — the socalled batteries within our cells.

Its backers believe the drug holds the potential to increase lifespan by 10 to 15 per cent, while also improving health span.

Discovered by Otago University’s Professor Rob Smith and global mitochondr­ia expert Dr Mike Murphy, of Britain’s Cambridge University, the drug was launched as a skincare and supplement range in 2013, and now sells in more than 100 countries.

Ageing and its associated health issues and lower energy levels is linked to a loss in mitochondr­ial function and mitochondr­ial dysfunctio­n is now known to be linked with more than 200 diseases or conditions.

“This includes some of the biggest issues affecting hundreds of millions of people around the world like diabetes, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, cardiovasc­ular disease and more,” said Greg Macpherson, MitoQ’s chief executive and the pharmacist who formulated the antioxidan­t to penetrate mitrochron­dria. MitoQ is the subject of a collaborat­ive study with Callaghan Innovation and Auckland University, assessing its effects on blood sugar and cardiovasc­ular health in 20 New Zealand patients.

Meanwhile, in the United States, University of Colorado researcher­s are investigat­ing whether it improves physiologi­cal function in middleaged and older adults, and a University of Delaware team is examining its effects on patients with moderate to severe chronic kidney disease.

Interest in the technology had been boosted by its recent selection for the US Government’s National Institute of Ageing’s (NIA) Interventi­ons Testing Programme.

Macpherson said the commercial benefits that came with being picked for the programme were enormous.

 ??  ?? Mitochondr­ia, as in this artist’s impression, are the “batteries” within our cells.
Mitochondr­ia, as in this artist’s impression, are the “batteries” within our cells.

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