The Press

The challenge of making medicine

- MADISON REIDY

Innovation and safety come hand in hand when you are regulating new drugs to combat untreatabl­e diseases.

It’s a process AFT Pharmaceut­icals founder Hartley Atkinson knows all too well. He said regulators had an ‘‘about right’’ balance of caution and encouragem­ent towards innovation in the pharmaceut­ical industry.

‘‘If you have got something new, innovative and different, you do also need to know it is safe.’’

He created Maxigesic, which combines paracetamo­l and ibuprofen in a pain relief tablet, and an antibacter­ial cream, Crystaderm, that does not fuel antibiotic resistance.

Atkinson has licensed a nasal spray device that delivers 20 times more medicine than current nasal sprays and could be used instead of intravenou­s drips in hospitals.

AFT’s Hylo-Fresh eye drops are created by robots in a German factory, and Atkinson is in the process of testing a topical treatment called Pascomer to cure the rare hereditary skin condition Angiofibro­mas.

It was important to have innovative products in healthcare because it was profitable for pharmaceut­ical companies to give customers options, Atkinson said.

‘‘There is this challenge; you are talking about business, but you are talking about people. The two are not totally divorced.’’

He said drug companies had been pushing to find treatments for incurable diseases in recent years.

But money is a barrier to creating new medicine, Atkinson said.

Hence AFT’s decision to publicly list on the New Zealand and Australian stock exchanges last year.

He said New Zealand has not appreciate­d his company’s costeffect­ive research and developmen­t strategy.

‘‘We developed a drug delivery device probably with $2 million to $3m. The big guys would spent $30m or $40m and get the same result.’’

His research and developmen­t staff work in groups of four to five people so they can act like a startup business, he said.

‘‘When groups get too big, people can kill an idea.’’

AFT could only cure what it could afford to, Atkinson said.

No New Zealand company could ever cure cancer because it would cost too much, he said.

The Fairfax Media business innovation series runs in partnershi­p with Callaghan Innovation.

 ?? PHOTO: LAWRENCE SMITH/ FAIRFAX NZ ?? Dr Hartley Atkinson spends plenty of time in talks with global drug regulators, which is a necessary step in bringing products to market.
PHOTO: LAWRENCE SMITH/ FAIRFAX NZ Dr Hartley Atkinson spends plenty of time in talks with global drug regulators, which is a necessary step in bringing products to market.

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