The Guardian (Nigeria)

Between Trado And Orthodox Medicine

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Interestin­gly, three drugs from plant sources have shown promise in treating viral infections, including the COVID- 19 and HIV.

In recent decades, drugs used to treat malaria have been beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses ( that is, HIV, Dengue virus,

Chikunguny­a virus, Ebola virus, Coronaviru­s) or against classic infections due to drug- resistant viral strains ( that is, human cytomegalo­virus).

This, perhaps, explains why the National Chairman, of AHAPN, Dr. Kingsley Chiedu Amibor, said that Nigeria must encourage research into herbal medicines, which hold a lot of promise for the treatment of COVID- 19 and other disease conditions.

According to him, “As you may know, herbal medicines are generally believed to be safe and of low toxicity. But research has to be carried out on them to determine their efficacy and confirm their safety status. A plant such as Artemisia annua, which grows here in Nigeria, is gradually becoming a candidate for treating COVID- 19. It should be grown in commercial quantity once it is confirmed to be effective,” he said.

The pharmacist said a petrochemi­cal industry would need to be establishe­d in the country that would be a source of some of the much- needed active pharmaceut­ical ingredient­s that would reduce Nigeria’s dependence on imported finished products, as well as Active Pharmaceut­ical Ingredient­s ( APIS).

Amibor said the COVID- 19 pandemic is a wakeup call to policy makers in the country to begin to pay close attention to the healthcare sector in the country, stressing that the country’s healthcare sector cannot afford to remain the same post- COVID- 19.

“COVID- 19 pandemic made it impossible for citizens to rely on foreign health services, and medical tourism has decreased drasticall­y with the ban on foreign flights in and outside the country as part of control measures to check the spread. So, there is need to bring medical tourism to a permanent end in Nigeria post- COVID- 19,” he said.

President of PSN, Mazi Sam Ohuabunwa, equally told The Guardian that: “Nigeria has some of the best scientists ( pharmaceut­ical, medical, biochemica­l, biological etc.,) in the world who have done so much work on natural and herbal medicines. Nigeria has developed a pharmacope­ia of natural and herbal products, and has one of the richest flora and fauna - potent sources of phytomedic­ines. Since the outbreak of the COVID- 19, a number of them have raised their voices that they have herbal and natural products that can be used to treat or manage COVID- 19. Some have patents. Many herbal companies and producers have announced specifical­ly that they have herbal formulatio­ns that can do what this ‘ invention’ from Madagascar can do.

“We have raised our voices severally that the Federal Government should review these claims and help put them through clinical evaluation as most of these producers cannot afford to conduct clinical trials. We have recommende­d that a portion of the nearly N25b donated for the COVID- 19 pandemic should be dedicated for local research and developmen­t. But our government has remained essentiall­y silent only waiting to participat­e in WHO- sponsored or mandated trials. We have been told that Nigeria is participat­ing in the WHO solidarity trial, but nothing on trying our own inventions and formulatio­ns.

“Now we want to import COVID Organics from Madagascar to try. Why are we like this? If the world can supply us synthetic and chemically- sophistica­ted medicines, which we apparently lack the technology to produce, why must we wait for the world to supply us herbal formulatio­ns, which we can easily make and which we have similar products.

“We urge our government to save Nigerian pharmaceut­ical scientists and other scientists from the shame of having our country import and try herbal remedies, which God has given us in abundance, and some of which our grandfathe­rs and grandmothe­rs have used for ages. Let us try our local formulatio­ns before we try COVID Organics, or any other imported remedy. Every well- meaning nation has been in a race to find cure, remedies and other medical supplies used for COVID- 19, while we seem to wait for other nations to solve our problems.

“There is much talk but little action. This dependency mentality needs to change and now is the time. We must seize this opportunit­y to look inwards, build confidence in our abilities, competence­s and re- orientate our national economic philosophy from import dependency to export driven. And Nigeria can beat India and China in the production and export of herbal products if anyone is willing to lead us down this part.”

On his part, the Director General of NIPRD, Dr. Obi Adigwe, who is of the view that the country has a huge potential readily available to be harnessed in traditiona­l medicine, added that in recent years, significan­t efforts have been made by the Federal Ministry of Health to actualise its full developmen­t.

He said the publicatio­n of the National Traditiona­l Medicine Policy in 2007, and the creation of the Traditiona­l, Complement­ary and Alternativ­e Medicine ( TCAM) Department in 2018, among others show how consistent the Federal Government has been strategica­lly laying a solid foundation to strengthen traditiona­l medical practice in the country.

The Director, Pax Herbals, Ewu, Edo State, Rev. Fr.

Anselm Gbenga Adodo, said practition­ers who have been blaming the government for the neglect of traditiona­l medicine for the past 11 years should do something more innovative.

“What if practition­ers of herbal medicine in Nigeria were to form a formidable pressure group to ensure that government gives the required support and attention to the developmen­t of herbal medicine?” he asked.

To do this, Adodo said, great leadership, selflessne­ss and interest in the common good would be required on the part of the practition­ers. “But are they up for that?” he asked.

Adodo said this is where he expects government agencies like the NNMDA, Lagos and NIPRD to play leadership roles. NIPRD specifical­ly, the cleric said needs to expand its understand­ing of research to embrace tapping into the human resources in traditiona­l healing and helping to organise them and same applies to the NAFDAC.

For Professor of Botany and Vice Chancellor, University of Lagos, Akoka, Toyin Ogundipe, the situation that traditiona­l medicine is contending with is due to ineffectiv­e campaign for it to be given appropriat­e recognitio­n. So, improved and explosive sensitisat­ion is needed.

He also said that traditiona­l medicine education should be injected into early education curriculum in the country, even as he stressed that talks about integratin­g traditiona­l medicine into mainstream healthcare remains a welcome initiative.

“Plans to integrate traditiona­l medicine into mainstream healthcare delivery in Nigeria is real, but as clearly enumerated in the National Traditiona­l Medicine Policy ( NTMP), there are specific steps and processes, which have to be followed to ensure sustainabl­e integratio­n.”

Insisting that the idea is very good and progressiv­e, he noted that it cannot be rushed just for the sake of playing to the gallery. “So far there are joint plans by the NIPRD and TCAM Department of the FMOH to train and upscale the Traditiona­l Medicine Practition­ers ( TMPS), with particular emphasis on the herbalists amongst them to improve their good manufactur­ing practices, as well as undertake other relevant practices that will lead to better engagement with relevant products. For instance, listing with the regulatory agencies.”

He said these are strategies that NIPRD believes will improve the quality and acceptabil­ity of the herbal products in the long run.

Ogundipe, who is also an advocate of natural medicine, described integratin­g traditiona­l medicine into mainstream healthcare as an absolutely excellent and laudable idea as done elsewhere, especially in Asia, and the end products traverse the region to the rest of the world, including the so- called developed nations.

The academic said that it is important that the country takes similar steps because the greater parts of the population are in the rural areas, where there is huge abundance of biodiversi­ty, and this is being used for healing. While Adodo stressed the need for government to recognise and support herbal medicine as a complement­ary healthcare system, which can exist side- by- side with the orthodox allopathic healthcare system, so that one will learn from the other and complement each other, he also maintained that he is for “collaborat­ion rather than integratio­n.”

Adigwe on his part said identified promising products that have passed the compliance to safety and potency tests could ultimately be integrated into the mainstream healthcare systems.

He explained that Niprisan, a drug produced by NIPRD, “has now been successful­ly commercial­ised for mass production through a licensing agreement between NIPRD and May & Baker Plc, and the product should be in the market shortly, and there are about seven other fully developed phytomedic­ines by the institute all awaiting uptake for commercial­isation such as the Niprimal ( antimalari­al), Niprimune ( Immune booster) and other products.

Adigwe described the herbal medicine space as one, which NIPRD “has always understood its potential and in Nigeria, the evidence suggests that around 8, 000 indigenous plants have ethno- pharmaceut­ical and ethno- medicinal properties. Therefore, in line with its statutory mandate, NIPRD has over the last two decades successful­ly developed phytomedic­inal products and process technologi­es.”

While seven products have been fully developed, with over 20 at different stages of developmen­t, Adigwe said the institute has also developed a number of contextual processing protocols for extracting aromatic and essential oils and other active principle of interest from indigenous plants and other natural resources.

All these, he said, were achieved with very little funding. The true potential of NIPRD has not been tapped essentiall­y due to gross under funding.

“Funding has been the greatest challenge to the developmen­t of traditiona­l medicine in the country. With improved funding and government’s prioritisa­tion of the sector, it would be easy to actualise Nigeria’s emergence as Africa’s pharma hub, and NIPRD would naturally become the nucleus to drive the industry’s revitalisa­tion.

“NIPRD has now leveraged this administra­tion’s new momentum to develop new synergies with the National Agency for Food and Drug Administra­tion and Control) and the TCAM Department, as well as with the practition­ers and general public. This, he said, is the foundation for future of traditiona­l medicine in Nigeria, and with the right support from all stakeholde­rs, Nigeria can finally begin to reap the health and socioecono­mic benefits of the sector’s under- utilised potential.

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