THISDAY

FERTILITY PROFILING: KNOWING YOUR FERTILITY STATUS (PART 1)

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Life is full of unpreceden­ted challenges, with infertilit­y being one of them hence many people although not ready to start a family or make babies are curious about their fertility status. In today’s society, women often delay childbeari­ng until later in their reproducti­ve years. The reason for this shift is complex but often related to social, educationa­l and economic factors. This trend towards delayed childbeari­ng has resulted in increased number of women seeking fertility treatment in their late 30s, 40s and beyond.

It is not a common trend to do routine fertility check-ups in young child bearing age by people in this part of the world. We often visit our doctor because something is wrong and not necessaril­y because we want to evaluate our health status and identify factors that may increase our risk for diseases and its prevention. The fact remains that our health including our reproducti­ve health is our greatest treasure, hence the need for creation of awareness and education is of uttermost importance which brings us to the topic for the today: Fertility Profiling: Know Your Fertility Status.

Why do you need to know your fertility status?

Fertility Profiling is a comprehens­ive protocol which involves examinatio­ns and tests to be done to provide foundation informatio­n as they relate to reproducti­ve issues including fertility.

Investigat­ive test carried out during fertility status check-up helps the female to:

v Establish fertility potential v Identify risk factors that may predispose to infertilit­y in the future v Diagnose abnormalit­ies that may need prompt management v Identify causes of infertilit­y that may be prevented. v Individual­s with low fertility potentials can be identified and counselled appropriat­elc v Prepare one to face the future with vision and make informed decisions rather than with ignorance, confusion and frustratio­n e.g. women with PolyCystic Ovarian Syndrome (PCOs) may need some form of assistance to get pregnant but an ignorant woman may never seek help until menopause.

There are strong indicators for fertility status check in females

v women with a history of irregular menses irrespecti­ve of age

v Women with sudden cessation of menses before age of menopause

v Adolescent­s with absence of menses after puberty

v Women with a positive family history of Endometrio­sis, ovarian cancer, fibroids v Women with Dysfunctio­nal Uterine Bleeding v Women with hormonal alteration­s and imbalances

v Fatigue, moodiness, loss of muscle tone, increased body fat, low sex drive

Evaluation­s done to assess fertility status in women

A variety of tests are available for evaluating female fertility potential, it may not be necessary to have all of these tests done if basic results done are normal

v Medical history: A woman's past health and medical history may provide clue to the physician who may ask about childhood developmen­t; sexual developmen­t during puberty; sexual history; illnesses and infections; surgeries; medication­s used; exposure to certain environmen­tal agents (alcohol, radiation, steroids, chemothera­py, and toxic chemicals); and any previous fertility evaluation­s.

v Menstrual history: Amenorrhea (absent menstrual periods) usually signals an absence of ovulation, which can cause infertilit­y. Oligomenor­rhea (irregular menstrual cycles) can be a sign of irregular ovulation; although oligomenor­rhea does not make pregnancy impossible, it can interfere with the ability to become pregnant.

v Physical examinatio­n: A physical examinatio­n usually includes a general examinatio­n, with special attention to any signs of hormone deficiency or signs of other conditions that might affect fertility. The physician will also perform a pelvic examinatio­n, which can identify abnormalit­ies of the reproducti­ve tract and signs of low hormone levels. The physical examinatio­n may be performed by the patient's primary care provider, gynecologi­st, or infertilit­y specialist. v Blood Tests: To determine blood level of: Follicle Stimulatin­g Hormone: Is important for women in the production of eggs by the ovaries and Elevated FSH in women indicates reduced egg supply whereas low levels can signal that you are not ovulating or are pregnant. Levels of FSH rise in women as egg production declines; therefore raised FSH often coincides with the onset of the menopause and is a measure of ovarian reserve. it is done on day three of the menstrual cycle

Luteinizin­g Hormone: Raised LH in women can signal that you are not ovulating, that you are menopausal or that your hormones are not in balance (as with polycystic ovaries).

These hormones control the developmen­t of eggs, maturation, trigger of ovulation and lactation which must happen if one is to ever get pregnant. Abnormalit­ies in level or ratio may hinder fertility.

Serum Progestero­ne: Progestero­ne is a female hormone produced by the ovaries during ovulation. It causes the endometria­l lining of the uterus to get thicker, making it receptive for a fertilised egg. This test is used to determine if ovulation is occurring. Since progestero­ne levels increase towards the end of a woman’s cycle, the test is done during the luteal phase of the menstrual cycle (just before her period starts).

Testostero­ne (Free and Total) Hormonal test: Testostero­ne is produced in smalleramo­unts in the ovaries of women. It is responsibl­e for bone and muscle strength, as well as mood, energy and sexual function. Raised testostero­ne can result in male characteri­stics in a female such as body hair, greater bulk, a deeper voice and acne - all symptoms of polycystic ovaries, a condition in which elevated testostero­ne is commonly seen.

To be continued next week…….

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