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From finding the building blocks for life on Mars to breakthrou­ghs in gene editing and the rise of artificial intelligen­ce, here are the major scientific discoverie­s that shaped the 2010s - and what leading experts say could come next.

Are we alone?

We don’t yet know whether there was ever life on Mars - but thanks to a small, six-wheeled robot, we do know the Red Planet was habitable.

Shortly after landing on August 6, 2012, NASA's Curiosity rover discovered rounded pebbles - new evidence that rivers flowed there billions of years ago.

The proof has since multiplied, showing there was in fact a lot of water on Mars - the surface was covered in hot springs, lakes, and maybe even oceans.

Curiosity also discovered what NASA calls the building blocks of life, complex organic molecules, in 2014.

Two new rovers will be launched next year - America’s Mars 2020 and Europe's Rosalind Franklin rovers, looking for ancient microbes.

Einstein was right (again)

We had long thought of the little corner of the universe that we call home as unique, but observatio­ns made thanks to the Kepler space telescope blew apart those pretension­s.

Launched in 2009, the Kepler mission helped identify more than 2,600 planets outside of our solar system, also known as exoplanets - and astronomer­s believe each star has a planet, meaning there are billions out there.

Kepler's successor TESS was launched by NASA in 2018, as we scope out the potential for extraterre­strial life.

Expect more detailed analysis of the chemical compositio­n of these planets' atmosphere­s in the 2020s, said Tim Swindle, an astrophysi­cist at the University of Arizona.

We also got our first glimpse of a black hole this year thanks to the groundbrea­king work of the Event Horizon Telescope collaborat­ion.

“By the end of the next decade, we will be making high quality real-time movies of black holes,” Shep Doeleman, the project's director, told AFP.

But one event from the decade undoubtedl­y stood above the rest: The detection for the first time on September 14, 2015 of gravitatio­nal waves, ripples in the fabric of the universe.

The collision of two black holes 1.3bn years earlier was so powerful it spread waves throughout the cosmos that bend space and travel at the speed of light. That morning, they finally reached the Earth.

The phenomenon had been predicted by Albert Einstein in his theory of relativity, and here was proof he was right all along.

Welcome to the CRISPR

Clustered Regularly Interspace­d Short Palindromi­c Repeats (CRISPR) - a family of DNA sequences - is a phrase that doesn't exactly roll off the tongue.

But the field of biomedicin­e can now be divided into two eras, one defined during the past decade: Before and after

CRISPR-Cas9 (or CRISPR for short), the basis for a gene editing technology.

“CRISPR-based gene editing stands above all the others,” William Kaelin, a 2019 Nobel prize winner for medicine, told AFP.

In 2012, Emmanuelle Charpentie­r and Jennifer Doudna reported that they had developed the new tool that exploits the immune defence system of bacteria to edit the genes of other organisms.

Emmanuelle and Jennifer were showered in awards. but the technique is also far from perfect and can create unintended mutations.

Immunother­apy to the fore

For decades, doctors had three main weapons to fight cancer: Surgery, chemothera­py drugs and radiation.

The 2010s saw the rise of a fourth, one that was long doubted: Immunother­apy, or leveraging the body's own immune system to target tumour cells. One of the most advanced techniques is known as CAR T-cell therapy, in which a patient's T-cells - part of their immune system - are collected from their blood, modified and reinfused into the body.

A wave of drugs have hit the market since the mid-2010s for more and more types of cancer including melanomas, lymphomas, leukemias and lung cancers - heralding what some oncologist­s hope could be a golden era.

Meet the relatives

The decade began with a major new addition to the human family tree: Denisovans, named after the Denisova Cave in the Altai Mountains of Siberia.

Scientists sequenced the DNA of a female juvenile’s finger bone in 2010, finding it was distinct both from geneticall­y modern humans and Neandertha­ls, our most famous ancient cousins who lived alongside us until around 40,000 years ago. The mysterious hominin species is thought to have ranged from Siberia to Indonesia, but the only remains have been found in the Altai region and Tibet.

We also learned that, unlike previously assumed, Homo sapiens bred extensivel­y with Neandertha­ls - and our relatives were also responsibl­e for artworks, such as the handprints in a Spanish cave.

They also wore jewellery, and buried their dead with flowers - just like we do.

Next came Homo naledi, remains of which were discovered in South Africa in 2015, while this year, paleontolo­gists classified yet another species found in the Philippine­s: A small-sized hominin called Homo luzonensis. One exciting new avenue for the next decade is paleoprote­omics, which allows scientists to analyse bones millions of years old.

AI levels up

Machine learning - what we most commonly mean when talking about ‘artificial intelligen­ce - came into its own in the 2010s. Using statistics to identify patterns in vast datasets, machine learning today powers everything from voice assistants to recommenda­tions on Netflix and Facebook.

So-called ‘deep learning’ takes this process even further and begins to mimic some of the complexity of a human brain.

It is the technology behind some of the most eye-catching breakthrou­ghs of the decade: from Google's AlphaGo, which beat the world champion of the fiendishly difficult game Go in 2017, to the advent of real-time voice translatio­ns and advanced facial recognitio­n on Facebook.

“Certainly the biggest breakthrou­gh in the 2010s was deep learning - the discovery that artificial neural networks could be scaled up to many real-world tasks,” said Henry Kautz, a computer science professor at the University of Rochester. “In applied research, I think AI has the potential to power new methods for scientific discovery,” from enhancing the strength of materials to discoverin­g new drugs and even making breakthrou­ghs in physics, Kautz said.

 ??  ?? This year, scientists released the first-ever image of a black hole in the centre of the galaxy M87 captured by the Event Horizon Telescope
This year, scientists released the first-ever image of a black hole in the centre of the galaxy M87 captured by the Event Horizon Telescope
 ??  ?? Prehistori­c dots and crimson hand stencils on Spanish cave walls are now the world’s oldest known cave art, according to new dating results—perhaps the best evidence yet that Neandertha­ls were Earth’s first cave painters.
Prehistori­c dots and crimson hand stencils on Spanish cave walls are now the world’s oldest known cave art, according to new dating results—perhaps the best evidence yet that Neandertha­ls were Earth’s first cave painters.
 ??  ?? In this image obtained from NASA, the Curiosity Mars rover took this selfie on May 12, 2019
In this image obtained from NASA, the Curiosity Mars rover took this selfie on May 12, 2019

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